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CCDC134 Knockout Cell Lines

Gene: CCDC134

Official Full Name: coiled-coil domain containing 134provided by HGNC

Gene Summary: Involved in regulation of ossification. Located in cytosol and intracellular membrane-bounded organelle. Implicated in osteogenesis imperfecta. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO20884 CCDC134 Knockout cell line (HeLa) Human CCDC134 1:3~1:6 Negative Online Inquiry
KO20885 CCDC134 Knockout cell line (HCT 116) Human CCDC134 1:2~1:4 Negative Online Inquiry
KO20886 CCDC134 Knockout cell line (HEK293) Human CCDC134 1:3~1:6 Negative Online Inquiry
KO20887 CCDC134 Knockout cell line (A549) Human CCDC134 1:3~1:4 Negative Online Inquiry

Background

CCDC134 Gene Knockout Cell Lines are specialized cellular models engineered to lack the CCDC134 gene, a critical component involved in various cellular processes, including cilia formation and maintenance, as well as several pathways influencing development and cellular signaling. By employing advanced CRISPR-Cas9 genome editing technology, these knockout cell lines facilitate the study of gene function and the physiological consequences of CCDC134 ablation.

The primary mechanism of action for the CCDC134 knockout lies in its reduction of gene expression, allowing researchers to ascertain the gene's role in cellular behavior under controlled experimental conditions. This insight can reveal vital interactions within signaling pathways, elucidating mechanisms governing developmental biology and disease pathology. Moreover, as the loss of CCDC134 can lead to observable phenotypic changes, this tool is invaluable for dissecting the biological ramifications of gene disruptions.

Scientific importance extends across various applications, ranging from fundamental research in molecular biology to potential uses in clinical settings where understanding gene function can inform therapeutic strategies, especially in regenerative medicine or cancer research. By providing a clear genetic background, these cell lines offer a robust platform for drug screening, toxicity testing, and biomarker discovery.

One of the key advantages of the CCDC134 Gene Knockout Cell Lines is their specificity, which reduces off-target effects often associated with other genetic manipulation techniques. Additionally, their creation adheres to strict quality control measures ensuring the reliability and reproducibility of experimental outcomes. This specificity can lead to faster, more accurate results, streamlining the research process.

For researchers and clinicians, CCDC134 Gene Knockout Cell Lines represent an essential resource that empowers deeper understanding of cellular dynamics and gene functions. By choosing this product, users benefit from a well-characterized and validated model that can significantly enhance the quality of their work.

Our company specializes in high-quality biological products, backed by a commitment to innovation and supporting the scientific community with tools that advance research and therapeutic development. With our expertise and advanced technologies, we ensure that you have access to the best models for your research needs.

Please note that all services are for research use only. Not intended for any clinical use.

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