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CCDC12 Knockout Cell Lines

Gene: CCDC12

Official Full Name: coiled-coil domain containing 12provided by HGNC

Gene Summary: Predicted to be located in nucleoplasm. Predicted to be part of U2-type spliceosomal complex and post-mRNA release spliceosomal complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21921 CCDC12 Knockout cell line (HeLa) Human CCDC12 1:3~1:6 Negative Online Inquiry
KO21922 CCDC12 Knockout cell line (HCT 116) Human CCDC12 1:2~1:4 Negative Online Inquiry
KO21923 CCDC12 Knockout cell line (HEK293) Human CCDC12 1:3~1:6 Negative Online Inquiry
KO21924 CCDC12 Knockout cell line (A549) Human CCDC12 1:3~1:4 Negative Online Inquiry

Background

CCDC12 Gene Knockout Cell Lines are specialized cellular models created through precise gene editing techniques that completely abrogate the expression of the CCDC12 gene, which encodes a protein implicated in various cellular processes, including intracellular transport and cytoskeletal organization. These engineered cell lines serve as critical tools for researchers aiming to elucidate the functional roles of CCDC12 in health and disease, particularly in studies related to cancer, developmental biology, and cell signaling pathways.

The key function of CCDC12 Gene Knockout Cell Lines lies in their ability to provide insights into the molecular mechanisms driven by the CCDC12 gene. By observing the phenotypic and molecular changes that occur in these knockout models, scientists can dissect the role of CCDC12 in crucial cellular activities such as cell proliferation, differentiation, and response to external stimuli. Mechanistically, the absence of the CCDC12 protein allows for the exploration of compensatory pathways and alternative signaling routes, thereby enhancing our understanding of cellular homeostasis and pathology.

In the scientific community, the relevance of CCDC12 Gene Knockout Cell Lines is underscored by their application in both basic research and therapeutic development. These models enable researchers to identify potential drug targets and biomarkers that could lead to novel treatment strategies for diseases characterized by dysregulated CCDC12 expression, making them invaluable in a clinical translational context.

Compared to alternative models that may not fully represent the biological consequences of gene disruption, the CCDC12 Gene Knockout Cell Lines offer a high degree of specificity and reliability. The precision of gene editing assures that the knockout is complete, allowing for confident interpretations of experimental outcomes, which is often challenging in less refined systems.

For researchers and clinicians alike, these cell lines provide a streamlined approach to studying the complexities of gene function, accelerating discovery processes and enhancing experimental rigor. The value they offer is particularly significant for projects targeting pathways linked to CCDC12, facilitating advancements in both therapeutic and academic research.

Backed by years of expertise in cell line development and molecular biology, our company is dedicated to providing cutting-edge biological tools that empower the scientific community. We are committed to delivering high-quality products that not only meet but exceed the expectations of our users, ensuring that they have access to the latest innovations in gene editing technology.

Please note that all services are for research use only. Not intended for any clinical use.

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