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CCDC102B Knockout Cell Lines

Gene: CCDC102B

Official Full Name: coiled-coil domain containing 102Bprovided by HGNC

Gene Summary: Enables protein serine/threonine kinase binding activity. Involved in centriole-centriole cohesion. Located in centriole. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18974 CCDC102B Knockout cell line (HeLa) Human CCDC102B 1:3~1:6 Negative Online Inquiry
KO18975 CCDC102B Knockout cell line (HCT 116) Human CCDC102B 1:2~1:4 Negative Online Inquiry

Background

CCDC102B Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to facilitate studies on the CCDC102B gene, which is implicated in various cellular processes, including ciliogenesis and microtubule dynamics. By employing CRISPR-Cas9 technology, these cell lines allow for the complete knockout of the CCDC102B gene, providing researchers with a powerful tool to investigate its functional significance.

The key functions of the CCDC102B Gene Knockout Cell Lines stem from their ability to model the loss of CCDC102B expression, enabling the examination of alterations in cellular behavior, signaling pathways, and associated phenotypic changes. This knockout approach paves the way for elucidating the role of CCDC102B in critical biological processes, such as cell-cycle regulation, signaling cascades, and the maintenance of cellular structure.

The scientific importance of these cell lines is profound, as they serve as instrumental models in diseases linked to ciliary dysfunction, such as respiratory and developmental disorders. In clinical and research settings, these knockout lines enable high-throughput screenings for drug discovery, studying gene interactions, and assessing the impact of specific genetic mutations related to human health.

Compared to traditional methods such as RNA interference, CCDC102B Gene Knockout Cell Lines provide a more robust and permanent loss-of-function model. This permanent alteration allows for clearer interpretations of results and increases reproducibility across experiments. Additionally, these cell lines are adaptable for various experimental conditions, including drug treatment and environmental changes, enhancing their utility in diverse research scenarios.

For researchers and clinicians, the CCDC102B Gene Knockout Cell Lines represent a significant advancement in understanding gene functions and developing potential therapeutic strategies. With our commitment to quality and innovation, our company specializes in providing high-fidelity genetic models, ensuring that our products meet the rigorous standards required for impactful scientific research and clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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