Home / CAVIN2 Knockout Cell Lines

CAVIN2 Knockout Cell Lines

Gene: CAVIN2

Official Full Name: caveolae associated protein 2provided by HGNC

Gene Summary: This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.[provided by RefSeq, Sep 2009]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34178 CAVIN2 Knockout cell line (HeLa) Human CAVIN2 1:3~1:6 Negative Online Inquiry
KO34179 CAVIN2 Knockout cell line (A549) Human CAVIN2 1:3~1:4 Negative Online Inquiry

Background

CAVIN2 Gene Knockout Cell Lines are genetically modified cell lines that have been engineered to disrupt the CAVIN2 gene, which plays a critical role in the formation and function of caveolae—small invaginations on the cell membrane involved in various cellular processes including signal transduction, lipid metabolism, and endocytosis. By knocking out the CAVIN2 gene, these cell lines provide a powerful tool for scientists seeking to elucidate the specific function of CAVIN2 in cellular physiology and its implications in pathological conditions, such as obesity and cardiovascular diseases.

The key function of the CAVIN2 gene knockout is to facilitate a deeper understanding of cellular mechanisms that involve caveolae. The loss of CAVIN2 leads to the disruption of caveolae structure and consequently affects the signaling pathways that rely on these structures, allowing researchers to study changes in cellular behavior. Through various assays, including proliferation, migration, and signaling studies, these knockout cell lines empower users to dissect the contributions of caveolae to health and disease more accurately.

The scientific importance of CAVIN2 knockouts is significant in both research and clinical settings, aiding in the exploration of disease mechanisms, drug responses, and cellular interactions. Researchers can leverage these models in studies aimed at discovering new therapeutic targets or understanding resistance mechanisms to existing treatments.

What sets CAVIN2 Gene Knockout Cell Lines apart from alternative models is their rigorously validated genetic modification, ensuring that users achieve consistent and reliable results. Additionally, the ability to analyze the consequences of CAVIN2 deficiency in a controlled environment minimizes confounding variables that are often present in in vivo models.

For researchers and clinicians seeking to advance their understanding of cell membrane dynamics and associated diseases, CAVIN2 Gene Knockout Cell Lines represent a vital advancement. Their utility in experimental research can pave the way for breakthroughs in therapeutic interventions.

Our company prides itself on providing high-quality biological products and services, backed by extensive expertise in genetic engineering and cellular biology. By choosing our CAVIN2 Gene Knockout Cell Lines, you gain access to a premier product designed to enhance your research and drive scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.