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CATSPERZ Knockout Cell Lines

Gene: CATSPERZ

Official Full Name: catsper channel auxiliary subunit zetaprovided by HGNC

Gene Summary: Predicted to be involved in flagellated sperm motility; male meiotic nuclear division; and sperm capacitation. Located in cytoplasm and sperm principal piece. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28706 CATSPERZ Knockout cell line (HCT 116) Human CATSPERZ 1:2~1:4 Negative Online Inquiry
KO28707 CATSPERZ Knockout cell line (A549) Human CATSPERZ 1:3~1:4 Negative Online Inquiry

Background

CATSPERZ Gene Knockout Cell Lines are genetically modified cell lines designed to specifically disrupt the CATSPERZ gene, which encodes a protein essential for sperm motility and fertility in various mammalian species. By employing CRISPR-Cas9 gene-editing technology, these knockout cell lines enable precise alterations in genetic sequences, allowing for the thorough investigation of the functional roles of CATSPERZ within reproductive health and developmental biology.

The primary mechanism of CATSPERZ knockout involves the non-homologous end joining repair pathway, effectively causing mutations that lead to the complete abrogation of the gene's expression. Researchers can then evaluate the physiological and biochemical impacts of CATSPERZ disruption on sperm function, aiding in the understanding of male fertility issues and the development of potential therapeutic targets. In clinical settings, these cell lines can serve as vital tools for screening pharmacological agents that could restore fertility or mitigate reproductive disorders.

One key advantage of CATSPERZ Gene Knockout Cell Lines is their specificity; unlike alternative methods which may affect multiple genes or cellular pathways, these lines provide a focused approach for studying CATSPERZ's distinct role. Additionally, they are designed to be highly reproducible, ensuring consistent results across multiple experiments.

For researchers and clinicians, the value of CATSPERZ knockout cell lines lies in their ability to shed light on fundamental reproductive biology and facilitate the development of interventions in fertility-related conditions. With a keen eye on innovation and scientific rigor, our company prides itself on creating high-quality biological products that empower the research community to exceed their scientific goals.

Please note that all services are for research use only. Not intended for any clinical use.

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