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CASZ1 Knockout Cell Lines

Gene: CASZ1

Official Full Name: castor zinc finger 1provided by HGNC

Gene Summary: The protein encoded by this gene is a zinc finger transcription factor. The encoded protein may function as a tumor suppressor, and single nucleotide polymorphisms in this gene are associated with blood pressure variation. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO19062 CASZ1 Knockout cell line (HeLa) Human CASZ1 1:3~1:6 Negative Online Inquiry
KO19063 CASZ1 Knockout cell line (HCT 116) Human CASZ1 1:2~1:4 Negative Online Inquiry
KO19064 CASZ1 Knockout cell line (HEK293) Human CASZ1 1:3~1:6 Negative Online Inquiry
KO19065 CASZ1 Knockout cell line (A549) Human CASZ1 1:3~1:4 Negative Online Inquiry

Background

CASZ1 Gene Knockout Cell Lines are genetically engineered cellular models that offer a targeted disruption of the CASZ1 gene, a key regulator involved in various developmental and cellular processes. These cell lines allow researchers to investigate the functional implications of CASZ1 loss, elucidating its role in cellular mechanisms such as differentiation, proliferation, and apoptosis. By employing methods like CRISPR-Cas9 gene editing, these cell lines ensure a precise modification, paving the way for detailed studies concerning the gene’s contribution to pathologies, including cancer and genetic disorders.

The primary mechanism by which CASZ1 Gene Knockout Cell Lines function lies in their ability to mimic human conditions where CASZ1 is aberrantly expressed or completely absent. Researchers can utilize these cell lines to assess the consequent phenotypic variations and cellular behaviors, facilitating a better understanding of disease mechanisms and potential therapeutic targets. This capability is crucial in both academic and clinical research, particularly in drug development and genetic therapy.

One of the significant advantages of using CASZ1 Gene Knockout Cell Lines is their specificity and reproducibility compared to traditional methods of gene disruption. Unlike conventional knockout techniques that may result in off-target effects, our gene-edited lines provide researchers with a reliable platform to validate findings and observe the direct effects of CASZ1 disruption on cellular pathways, ensuring high-quality data integrity.

For researchers and clinicians focused on advancing our understanding of gene function in health and disease, these cell lines represent a valuable tool. Their use can expedite research, enhance translational applications, and ultimately contribute to novel therapeutic developments.

Our company prides itself on a deep commitment to advancing genetic research, providing high-quality biological products backed by advanced technology and a thorough understanding of molecular biology, ensuring that you receive the best tools for your research needs.

Please note that all services are for research use only. Not intended for any clinical use.

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