Home / CARF Knockout Cell Lines

CARF Knockout Cell Lines

Gene: CARF

Official Full Name: calcium responsive transcription factorprovided by HGNC

Gene Summary: Enables DNA binding activity and DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in cellular response to calcium ion. Predicted to be located in granular component. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO19087 CARF Knockout cell line (HCT 116) Human CARF 1:2~1:4 Negative Online Inquiry
KO19088 CARF Knockout cell line (HEK293) Human CARF 1:3~1:6 Negative Online Inquiry
KO19089 CARF Knockout cell line (A549) Human CARF 1:3~1:4 Negative Online Inquiry

Background

CARF Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to assess the functional impact of the CARF gene, a critical player in cellular stress response and gene expression regulation. These knockout lines are created using CRISPR-Cas9 technology, which enables precise inactivation of the CARF gene in various cell types, thereby allowing for the elucidation of its role in biological pathways.

The primary mechanism of action involves the disruption of CARF's interplay with other nuclear proteins, leading to alterations in gene transcription, particularly under stress conditions. This disruption facilitates comprehensive studies on CARF's influence on apoptosis, cell cycle regulation, and tumorigenesis, providing researchers with valuable insights into cellular behavior and disease mechanisms.

These cell lines hold significant scientific importance, especially in cancer research, neurobiology, and studies related to metabolic disorders. By providing a model to study the phenotypic consequences of CARF gene deletion, researchers can explore potential therapeutic targets and biomarkers, bridging the gap between basic science and clinical applications.

Compared to traditional knockdown methods, CARF Gene Knockout Cell Lines offer improved specificity and stability of gene disruption, which not only enhances experimental reproducibility but also expedites data acquisition. Furthermore, these cell lines can be adapted for high-throughput screening applications, making them an essential tool in drug discovery and preclinical trials.

For researchers and clinicians, acquiring CARF Gene Knockout Cell Lines translates into access to a robust resource that empowers them to drive innovative research and accelerate advancements in understanding cellular responses. This capability is crucial for pushing the boundaries of current knowledge in molecular biology and therapeutic development.

Our company prides itself on its extensive expertise in the production of high-quality, genetically modified cell lines. With a focus on providing cutting-edge biological products, we are committed to supporting the scientific community’s goals by delivering reliable and innovative research solutions.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.