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CAPS Knockout Cell Lines

Gene: CAPS

Official Full Name: calcyphosineprovided by HGNC

Gene Summary: This gene encodes a calcium-binding protein, which may play a role in the regulation of ion transport. A similar protein was first described as a potentially important regulatory protein in the dog thyroid and was termed as R2D5 antigen in rabbit. Alternative splicing of this gene generates two transcript variants. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO04748 CAPS Knockout cell line (HeLa) Human CAPS 1:3~1:6 Negative Online Inquiry
KO04749 CAPS Knockout cell line (HCT 116) Human CAPS 1:2~1:4 Negative Online Inquiry
KO04750 CAPS Knockout cell line (HEK293) Human CAPS 1:3~1:6 Negative Online Inquiry
KO04751 CAPS Knockout cell line (A549) Human CAPS 1:3~1:4 Negative Online Inquiry

Background

CAPS Gene Knockout Cell Lines are engineered cellular models that have been meticulously developed to provide researchers with a powerful tool for gene function analysis and disease modeling. By utilizing CRISPR-Cas9 technology, these cell lines feature targeted disruptions of specific genes, allowing for precise investigation of gene roles in various biological processes or disease mechanisms. Each cell line is designed to knock out a specific gene of interest, facilitating studies related to gene expression, protein interactions, and functional assays.

The mechanism underlying the efficacy of CAPS Gene Knockout Cell Lines lies in their ability to replicate the phenotypic consequences of gene inactivation in a controlled environment. Researchers can perform loss-of-function experiments to elucidate pathways involved in cellular responses, drug resistance, or developmental biology. Furthermore, these models are invaluable in preclinical studies, as they allow for the assessment of therapeutic targets and the evaluation of new drug candidates.

The scientific importance of these cell lines extends across a broad spectrum of research areas including oncology, immunology, and neurobiology. They serve as essential platforms for understanding complex diseases at a molecular level, enabling scientists to dissect the contributions of specific genes to pathological states. In clinical settings, these knockout models can expedite the discovery of biomarkers and personalized treatment strategies.

One of the standout advantages of CAPS Gene Knockout Cell Lines is their stringent quality control and reproducibility compared to alternative models such as transient knockdowns or RNA interference. Each cell line is validated for gene deletion efficiency, off-target effects, and phenotypic characteristics, ensuring reliability and consistency in experimental outcomes.

For researchers and clinicians seeking innovative solutions to accelerate their studies, CAPS Gene Knockout Cell Lines represent an unparalleled asset. They offer an efficient, ethical, and effective means to investigate gene function comprehensively, paving the way for breakthroughs in understanding disease biology and therapeutic development.

With a commitment to excellence in biological products, our company leverages cutting-edge technology and extensive expertise in genetic engineering to deliver consistently high-quality cell models that meet the evolving needs of the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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