Gene: CAMKV
Official Full Name: CaM kinase like vesicle associatedprovided by HGNC
Gene Summary: Predicted to enable calcium/calmodulin-dependent protein kinase activity and calmodulin binding activity. Predicted to be involved in signal transduction. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane. Predicted to be active in cytoplasm; glutamatergic synapse; and postsynapse. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19109 | CAMKV Knockout cell line (HEK293) | Human | CAMKV | 1:3~1:6 | Negative | Online Inquiry |
CAMKV Gene Knockout Cell Lines are advanced cellular models specifically engineered for the targeted disruption of the CAMK2 (Calcium/Calmodulin-Dependent Protein Kinase Type II) gene. This genetic modification enables researchers to elucidate the roles of CAMK2 in various physiological and pathological processes, allowing for a deeper understanding of calcium signaling pathways and their implications in neurobiology, cardiac function, and inflammation.
The primary mechanism by which CAMKV Gene Knockout Cell Lines operate involves the CRISPR-Cas9 technology, which facilitates precise alterations in the genomic DNA of the host cell. By creating loss-of-function mutations in the CAMK2 gene, researchers can investigate changes in cell behavior, gene expression profiles, and signaling pathways. This molecular specificity enhances the accuracy of experimental outcomes, making these cell lines invaluable tools for dissecting complex biological interactions and disease mechanisms.
The scientific importance of CAMKV Gene Knockout Cell Lines is notable in both research and clinical settings, where they serve as a foundation for drug development, disease modeling, and therapeutic interventions. The ability to study CAMK2's contributions to conditions such as Alzheimer’s disease, heart failure, and cancer can lead to novel insights and applications in precision medicine. Their versatility allows for the examination of numerous cellular functions, including synaptic plasticity, apoptosis, and cellular metabolism.
Compared to alternative genetic manipulation strategies, the CRISPR-based CAMKV Gene Knockout Cell Lines offer several advantages, including higher efficiency, lower off-target effects, and more straightforward experimental design. This makes them particularly appealing for laboratories aiming for reproducibility and high-throughput screening capabilities.
For researchers and clinicians seeking to pioneer studies in molecular biology and therapeutic advancements, CAMKV Gene Knockout Cell Lines represent a significant investment. Their unique attributes not only streamline experimental workflows but also enhance the potential for transformative findings in the realms of disease research and drug discovery.
As a leader in the development of innovative biological products, our company is dedicated to providing high-quality, expertly engineered cell lines that meet the rigorous demands of contemporary scientific inquiry. Our commitment to excellence ensures that every product supports your mission to advance knowledge and improve health outcomes.
Please note that all services are for research use only. Not intended for any clinical use.
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