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CAMKMT Knockout Cell Lines

Gene: CAMKMT

Official Full Name: calmodulin-lysine N-methyltransferaseprovided by HGNC

Gene Summary: This gene encodes a class I protein methyltransferase that acts in the formation of trimethyllysine in calmodulin. The protein contains a AdoMet-binding motif and may play a role in calcium-dependent signaling. [provided by RefSeq, Sep 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO19110 CAMKMT Knockout cell line (HeLa) Human CAMKMT 1:3~1:6 Negative Online Inquiry
KO19111 CAMKMT Knockout cell line (HCT 116) Human CAMKMT 1:2~1:4 Negative Online Inquiry
KO19112 CAMKMT Knockout cell line (HEK293) Human CAMKMT 1:3~1:6 Negative Online Inquiry
KO19113 CAMKMT Knockout cell line (A549) Human CAMKMT 1:3~1:4 Negative Online Inquiry

Background

CAMKMT Gene Knockout Cell Lines are genetically engineered cellular models designed to silence the CAMKMT (Calcium/Calmodulin-Dependent Protein Kinase Methyltransferase) gene. By utilizing CRISPR-Cas9 technology, these cell lines offer researchers a powerful tool for investigating the underlying mechanisms of cellular signaling and function in various biological pathways. CAMKMT plays a crucial role in regulating calcium signaling, and its silencing through these knockout models provides insights into the effects of disrupted calcium homeostasis and its implications in health and disease.

The core function of CAMKMT Gene Knockout Cell Lines lies in their ability to mimic loss-of-function mutations found in the CAMKMT gene. The mechanisms employed include precise gene editing that allows for the elimination of the CAMKMT protein, leading to altered kinase activity and downstream signaling pathways. By examining these alterations, researchers can better understand the gene’s role in conditions such as cardiovascular diseases, neurodegenerative disorders, and cancer, where calcium signaling is often dysregulated.

Scientifically, these cell lines serve as vital tools in both research and clinical settings. They allow for high-throughput screening of potential therapeutic compounds targeting CAMKMT signaling pathways and provide a robust platform for studying cellular responses to drug treatments. Additionally, they contribute to advancing gene therapy approaches and personalized medicine by enabling in-depth genetic and phenotypic analyses.

Compared to alternative models, CAMKMT Gene Knockout Cell Lines offer enhanced specificity and reproducibility in studying the role of CAMKMT. Unlike conventional knockdown models, which may only partially inhibit gene expression, these knockout lines provide complete absence of the protein, leading to more definitive results in experimental assays. Furthermore, our cell lines are derived from widely-used host backgrounds, ensuring compatibility with existing research protocols.

The value of CAMKMT Gene Knockout Cell Lines to researchers and clinicians cannot be understated, as they open new avenues for understanding important signaling pathways, thereby facilitating the development of targeted therapies. Investing in these cell lines means equipping your laboratory with the necessary tools to stay at the forefront of genetic research and therapeutic innovation.

At [Your Company Name], we pride ourselves on our commitment to excellence in genetic engineering and the development of cutting-edge biological products. Our expertise lies in providing high-quality research tools that propel scientific discovery forward, ensuring our products meet the highest standards of reliability and performance for our clients.

Please note that all services are for research use only. Not intended for any clinical use.

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