Gene: CALCOCO1
Official Full Name: calcium binding and coiled-coil domain 1provided by HGNC
Gene Summary: Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; beta-catenin binding activity; and nuclear receptor coactivator activity. Involved in positive regulation of DNA-templated transcription and positive regulation of gene expression. Located in cytosol and nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19114 | CALCOCO1 Knockout cell line (HeLa) | Human | CALCOCO1 | 1:3~1:6 | Negative | Online Inquiry |
KO19115 | CALCOCO1 Knockout cell line (HCT 116) | Human | CALCOCO1 | 1:2~1:4 | Negative | Online Inquiry |
KO19116 | CALCOCO1 Knockout cell line (HEK293) | Human | CALCOCO1 | 1:3~1:6 | Negative | Online Inquiry |
KO19117 | CALCOCO1 Knockout cell line (A549) | Human | CALCOCO1 | 1:3~1:4 | Negative | Online Inquiry |
CALCOCO1 Gene Knockout Cell Lines are specialized cellular models that have had the CALCOCO1 gene selectively disabled through advanced CRISPR/Cas9 technology. This precise genetic manipulation enables researchers to examine the specific roles and functional consequences of the CALCOCO1 protein, which is implicated in various biological processes, including immune responses and cellular signaling pathways. The knockout of CALCOCO1 provides a powerful tool for dissecting its contribution to health and disease, making these cell lines invaluable for both basic and translational research.
In terms of function, the CALCOCO1 Gene Knockout Cell Lines allow scientists to study the downstream effects of CALCOCO1 deletion, providing insights into altered biological pathways, gene expression patterns, and protein interactions. By utilizing these cell lines, researchers can evaluate the gene's role in pathologies such as autoimmune diseases, cancer, and infections. This insight is critical for understanding how targeting CALCOCO1 could lead to innovative therapeutic approaches.
The scientific importance of these cell lines cannot be overstated. They serve as essential models for drug discovery, biomarker development, and functional genomics that contribute to the advancement of personalized medicine. Moreover, researchers in both academia and industry can utilize these cell lines to advance their understanding of immunological mechanisms, enhancing the development of new therapeutic strategies.
What sets CALCOCO1 Gene Knockout Cell Lines apart from alternatives is their validated gene disruption and robust phenotypic consistency. Each line undergoes thorough characterization, ensuring reliability in experimental outcomes. Additionally, they provide a unique opportunity for high-throughput screening processes vital for contemporary pharmacological research.
In summary, the CALCOCO1 Gene Knockout Cell Lines represent a unique and essential resource for researchers and clinicians focused on genetic, cellular, and molecular biology. Their potential to contribute to groundbreaking research makes them a critical addition to any laboratory engaged in contemporary biological studies. Our company prides itself on providing high-quality, reliable biological tools tailored to meet the specific needs of the research community, ensuring that our products empower scientific discovery effectively and efficiently.
Please note that all services are for research use only. Not intended for any clinical use.
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