Gene: CACNG7
Official Full Name: calcium voltage-gated channel auxiliary subunit gamma 7provided by HGNC
Gene Summary: The protein encoded by this gene is a type II transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type I TARP and a calcium channel gamma subunit. [provided by RefSeq, Dec 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19121 | CACNG7 Knockout cell line (A549) | Human | CACNG7 | 1:3~1:4 | Negative | Online Inquiry |
CACNG7 Gene Knockout Cell Lines are specially engineered cellular models that have had the CACNG7 gene inactivated, allowing researchers to explore the role of this gene in various biological processes and diseases. The CACNG7 gene encodes a protein that is crucial for synaptic function and neuronal signaling, particularly in the modulation of ion channels in the nervous system. By generating these knockout cell lines, scientists can investigate the gene's specific contributions to neurobiological pathways and mechanisms underlying conditions such as schizophrenia, autism spectrum disorders, and other neuropsychiatric diseases.
The primary function of the CACNG7 knockout cell lines revolves around the disruption of normal protein expression, permitting study of altered cellular behavior, signaling cascades, and gene interactions. Researchers can utilize these models to assess changes in synaptic plasticity, neurotransmitter release, and other critical neurophysiological parameters, effectively correlating the absence of CACNG7 with observed phenotypic variations.
The scientific importance of these cell lines extends to their application in drug discovery and development, especially in identifying potential therapeutic targets. Researchers can utilize these models to screen compounds for efficacy and safety in manipulating pathways linked to CACNG7, streamlining the path from bench to clinical application.
Compared to conventional models, CACNG7 Gene Knockout Cell Lines offer distinct advantages, such as the ability to replicate specific genetic modifications that may not be present in heterogeneous cell populations. This specificity enables more controlled studies, critical for elucidating gene functions and the effects of potential drugs with greater precision.
For researchers and clinicians alike, the CACNG7 Gene Knockout Cell Lines represent an invaluable tool in neurobiology and genetics, facilitating advancements in our understanding of complex diseases. Our company, with its robust expertise in genetic engineering and cellular biology, is committed to providing high-quality, reliable bioresearch tools that empower scientists to achieve their research objectives with confidence.
Please note that all services are for research use only. Not intended for any clinical use.
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