Gene: CABLES2
Official Full Name: Cdk5 and Abl enzyme substrate 2provided by HGNC
Gene Summary: Predicted to be involved in cell division and regulation of cell cycle. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25597 | CABLES2 Knockout cell line (HeLa) | Human | CABLES2 | 1:3~1:6 | Negative | Online Inquiry |
KO25598 | CABLES2 Knockout cell line (HCT 116) | Human | CABLES2 | 1:2~1:4 | Negative | Online Inquiry |
KO25599 | CABLES2 Knockout cell line (HEK293) | Human | CABLES2 | 1:3~1:6 | Negative | Online Inquiry |
KO25600 | CABLES2 Knockout cell line (A549) | Human | CABLES2 | 1:3~1:4 | Negative | Online Inquiry |
CABLES2 Gene Knockout Cell Lines are engineered cellular models specifically designed for the comprehensive study of the CABLES2 gene, known for its role in cell cycle regulation and cancer progression. These cell lines have undergone rigorous genetic modification techniques such as CRISPR-Cas9, resulting in a targeted deletion of the CABLES2 gene, providing researchers with a tool to investigate the gene's functions in various physiological and pathological contexts.
The key mechanism of the CABLES2 knockout involves the loss of its regulatory influence on the cell cycle, thereby enabling scientists to observe alterations in cell proliferation, apoptosis, and differentiation pathways. By utilizing these knockout cell lines, researchers can elucidate the downstream effects of CABLES2 deficiency on tumorigenesis, offering insights into potential therapeutic targets and biomarkers for cancer treatment.
The scientific value of CABLES2 Gene Knockout Cell Lines is underscored by their utility in both basic research and clinical applications. In laboratories, they serve as vital models for drug screening and validation of novel oncogenic pathways. Clinically, understanding the role of CABLES2 can inform personalized medicine approaches, particularly in cancers where its expression levels correlate with patient prognosis.
In comparison to traditional cell lines, our CABLES2 knockout models provide a unique advantage through their specificity and reproducibility, allowing for high-fidelity studies that are often difficult to achieve with non-targeted models. This level of precision not only enhances the reliability of experimental results but also accelerates the path from discovery to application.
For researchers and clinicians focusing on cancer biology and genetic regulation, our CABLES2 Gene Knockout Cell Lines represent an invaluable asset, offering a deeper understanding of cellular mechanisms and paving the way for innovative therapeutic strategies. Our company prides itself on a robust background in genetic engineering and cell line development, ensuring the highest quality and performance of our biological products to meet the diverse needs of the scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
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