Gene: CA13
Official Full Name: carbonic anhydrase 13provided by HGNC
Gene Summary: Predicted to enable carbonate dehydratase activity. Predicted to be involved in one-carbon metabolic process. Predicted to be located in intracellular membrane-bounded organelle and myelin sheath. Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19134 | CA13 Knockout cell line (HeLa) | Human | CA13 | 1:3~1:6 | Negative | Online Inquiry |
KO19135 | CA13 Knockout cell line (HCT 116) | Human | CA13 | 1:2~1:4 | Negative | Online Inquiry |
KO19136 | CA13 Knockout cell line (HEK293) | Human | CA13 | 1:3~1:6 | Negative | Online Inquiry |
CA13 Gene Knockout Cell Lines are genetically engineered cell lines that have been specifically designed to lack the expression of the CA13 gene, an important player in various physiological processes, including pH regulation and cellular signaling. These knockout models serve as invaluable tools for researchers aiming to dissect the functional roles of CA13 in health and disease by elucidating the downstream effects of its absence.
The key function of the CA13 knockout cell lines lies in their ability to mimic the pathological conditions associated with CA13 deficiency. By using CRISPR-Cas9 or other genome-editing techniques, these cell lines are rendered deficient in CA13, allowing for the study of altered biochemical pathways and cellular responses. Research utilizing these models can lead to a deeper understanding of how CA13 influences processes such as tumorigenesis, metabolic dysregulation, and neurodegenerative diseases.
Scientifically, CA13 gene knockout cell lines have significant applications in both academic and clinical research settings. They offer researchers a platform to test hypotheses regarding CA13’s role in disease phenomena, potentially leading to the identification of novel therapeutic targets. Furthermore, these cell lines facilitate drug screening and toxicity studies, allowing scientists to assess the impact of compounds on the pathways regulated by CA13.
Compared to traditional wild-type cell lines, CA13 gene knockout cell lines provide a unique advantage by enabling precise examination of gene function related to CA13. This specificity enhances the accuracy of research findings, making them more reproducible and relevant to human biology. Additionally, these cell lines are amenable to various assays, including gene expression analysis, protein interaction studies, and in vivo studies when used in more complex organisms.
For researchers and clinicians engaged in studying physiological and pathological mechanisms, CA13 gene knockout cell lines represent a powerful, cutting-edge tool that can accelerate discoveries in biomedical research. Our company, a leader in the development of gene-modified cellular models, prides itself on delivering high-quality, reliable cell lines that support innovative research. By choosing our CA13 gene knockout cell lines, you invest in a product backed by rigorous scientific methods and a commitment to advancing life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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