Gene: C1RL
Official Full Name: complement C1r subcomponent likeprovided by HGNC
Gene Summary: Predicted to enable serine-type endopeptidase activity. Predicted to be involved in zymogen activation. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO05919 | C1RL Knockout cell line (HeLa) | Human | C1RL | 1:3~1:6 | Negative | Online Inquiry |
KO05920 | C1RL Knockout cell line (HCT 116) | Human | C1RL | 1:2~1:4 | Negative | Online Inquiry |
KO05921 | C1RL Knockout cell line (A549) | Human | C1RL | 1:3~1:4 | Negative | Online Inquiry |
C1RL Gene Knockout Cell Lines are genetically engineered cell lines that have had the C1RL gene specifically disrupted using advanced genome-editing technologies, such as CRISPR-Cas9. These cell lines serve as valuable research tools for elucidating the biological functions of the C1RL gene, which is known to be implicated in the regulation of the complement system—a critical part of the immune response. By creating knockout models, researchers can systematically study the phenotypic consequences of C1RL disruption and dissect its role in various pathological conditions, including autoimmune diseases and inflammatory responses.
The core functionality of C1RL Gene Knockout Cell Lines revolves around providing researchers with a controlled environment to investigate the effects of C1RL gene absence. The knockout alters key signaling pathways, enabling scientists to analyze changes in cellular behavior, immune responses, and interactions with other proteins within the complement cascade. Such models can be pivotal for breaking new ground in immunology and therapeutic research, leading to insights that may inform drug development or gene therapies.
Scientific importance is highlighted by the growing recognition of the complement system's role in a myriad of diseases. C1RL is a focal point for studying complement dysregulation and its association with conditions like systemic lupus erythematosus and childhood cataracts. The C1RL Gene Knockout Cell Lines thus empower researchers and clinicians to uncover the mechanistic pathways involved and potentially identify novel therapeutic targets.
When compared to alternative knockout models, C1RL Gene Knockout Cell Lines stand out due to their precision and reproducibility facilitated by state-of-the-art editing techniques. They offer unparalleled experimental consistency and minimize variability, which is crucial for high-stakes research and clinical applications. Furthermore, these cell lines are supported by comprehensive characterization data, ensuring users can confidently translate findings into relevant biological contexts.
For researchers and clinicians seeking to advance their understanding of immune regulation and its implications in health and disease, C1RL Gene Knockout Cell Lines provide an essential resource. The investment in these cell lines can lead to critical breakthroughs in both academic research and therapeutic advancements. Our company, with a strong foundation in genomic technologies and a commitment to innovation, delivers high-quality biological products that support the evolution of science and medicine.
Please note that all services are for research use only. Not intended for any clinical use.
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