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C1QL4 Knockout Cell Lines

Gene: C1QL4

Official Full Name: complement C1q like 4provided by HGNC

Gene Summary: Predicted to enable identical protein binding activity. Predicted to act upstream of or within negative regulation of ERK1 and ERK2 cascade; negative regulation of fat cell differentiation; and negative regulation of fibroblast proliferation. Predicted to be located in extracellular space. Predicted to be part of collagen trimer. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO19302 C1QL4 Knockout cell line (HCT 116) Human C1QL4 1:2~1:4 Negative Online Inquiry
KO19303 C1QL4 Knockout cell line (HEK293) Human C1QL4 1:3~1:6 Negative Online Inquiry
KO19304 C1QL4 Knockout cell line (A549) Human C1QL4 1:3~1:4 Negative Online Inquiry

Background

C1QL4 Gene Knockout Cell Lines are genetically engineered cell models designed to lack the C1QL4 gene, a crucial component in various biological pathways, particularly in neuronal function and development. These knockout cell lines enable researchers to explore the role of C1QL4 in cellular mechanisms, including synaptogenesis, neuronal differentiation, and potential implications in neurodegenerative diseases. By providing a reliable system for the investigation of gene function, these cell lines facilitate a deeper understanding of the molecular basis of neurological disorders.

The key mechanism by which these C1QL4 knockout cell lines operate is through the targeted disruption of the C1QL4 gene using CRISPR-Cas9 technology. This method results in the absence of C1QL4 protein, allowing for the examination of cellular behaviors and pathways that are altered in its absence. Consequently, researchers can study gene interactions, signaling pathways, and even drug responses that would be impossible to investigate in unmodified cell lines where C1QL4 expression is present.

The scientific importance of C1QL4 Gene Knockout Cell Lines lies in their application across both basic and translational research. These models are vital for elucidating the biological functions of C1QL4 and assessing its potential as a therapeutic target in neurological diseases. Their relevance extends to drug discovery pipelines, where understanding the role of candidate genes can lead to innovative treatment strategies.

What sets C1QL4 Gene Knockout Cell Lines apart from alternative models is their specificity and robustness. Unlike traditional knockout methods that may result in off-target effects, the CRISPR-Cas9 technique ensures a high level of precision, making these cell lines more reliable for producing reproducible data. Moreover, they are designed for easy application across various platforms, facilitating integration into diverse experimental setups.

For researchers and clinicians, C1QL4 Gene Knockout Cell Lines represent an invaluable tool in the quest to unravel the complexities of neurobiology. Their unique ability to provide insights into gene-function relationships positions them as essential assets for anyone studying neuronal mechanisms or developing novel therapeutics.

With a commitment to excellence and innovation, our company specializes in creating high-quality biological products tailored to meet the rigorous demands of scientific research. We provide comprehensive support to help you maximize the potential of your studies, ensuring successful outcomes in your research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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