Gene: C17orf75
Official Full Name: chromosome 17 open reading frame 75provided by HGNC
Gene Summary: Involved in intracellular protein transport and vesicle tethering to Golgi. Located in cytoplasmic vesicle; cytosol; and trans-Golgi network. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19160 | C17orf75 Knockout cell line (HeLa) | Human | C17orf75 | 1:3~1:6 | Negative | Online Inquiry |
KO19161 | C17orf75 Knockout cell line (HCT 116) | Human | C17orf75 | 1:2~1:4 | Negative | Online Inquiry |
KO19162 | C17orf75 Knockout cell line (HEK293) | Human | C17orf75 | 1:3~1:6 | Negative | Online Inquiry |
KO19163 | C17orf75 Knockout cell line (A549) | Human | C17orf75 | 1:3~1:4 | Negative | Online Inquiry |
C17orf75 Gene Knockout Cell Lines are specialized cellular models engineered through precise gene editing techniques to inactivate the C17orf75 gene, which is implicated in various biological processes and disease states. This targeted knockout approach allows researchers to investigate the gene's function and its contributions to cellular behavior, signaling pathways, and disease mechanisms.
The key mechanism by which these cell lines function is based on CRISPR-Cas9 technology, which enables specific and irreversible modifications of the target gene sequence. By generating a knockout of C17orf75, researchers can observe the resultant phenotypic changes and dissect the gene's role in processes such as cellular proliferation, differentiation, and response to stressors. These insights are crucial for understanding disease pathology and for the development of therapeutic strategies.
The scientific importance of C17orf75 Gene Knockout Cell Lines lies in their application in both basic research and clinical settings. They serve as models for studying the pathogenesis of diseases associated with C17orf75 dysregulation, including certain cancers and metabolic disorders. Furthermore, these cell lines are integral in drug discovery and testing, as they allow for the evaluation of therapeutic targets and the efficacy of candidate compounds.
Compared to traditional cell lines that may exhibit variable gene expression profiles, C17orf75 Gene Knockout Cell Lines offer a high level of specificity and reliability. This precision reduces experimental variability and enhances reproducibility, making them preferable tools for rigorous scientific investigations.
Researchers and clinicians will find these cell lines invaluable as they provide a directed approach to unraveling complex biological systems and elucidating potential therapeutic avenues. The robust data generated from studies utilizing these knockout models can lead to transformative discoveries in health and disease.
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Please note that all services are for research use only. Not intended for any clinical use.
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