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C15orf48 Knockout Cell Lines

Gene: C15orf48

Official Full Name: chromosome 15 open reading frame 48provided by HGNC

Gene Summary: This gene was first identified in a study of human esophageal squamous cell carcinoma tissues. Levels of both the message and protein are reduced in carcinoma samples. In adult human tissues, this gene is expressed in the the esophagus, stomach, small intestine, colon and placenta. Alternatively spliced transcript variants that encode the same protein have been identified. [provided by RefSeq, Jun 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
GP00631 C15orf48 gRNA1-gRNA2 KO plasmid C15orf48 $850
KO00833 C15orf48 Knockout cell line(THP-1) Human C15orf48 1:2-1:4 Negative Online Inquiry
KO19177 C15orf48 Knockout cell line (HEK293) Human C15orf48 1:3~1:6 Negative Online Inquiry
KO19178 C15orf48 Knockout cell line (A549) Human C15orf48 1:3~1:4 Negative Online Inquiry

Background

C15orf48 Gene Knockout Cell Lines are specifically designed cellular models that facilitate the study of the C15orf48 gene's function by permanently disrupting its expression. This product provides researchers with a powerful tool for investigating the biological roles of this gene in various physiological and pathological contexts, including its potential implications in cancer biology and cellular signaling pathways.

The mechanism through which these cell lines operate involves the targeted disruption of the C15orf48 gene using CRISPR-Cas9 technology, resulting in the knockout of functional protein expression. By employing this precise gene-editing technique, researchers can generate a reliable and reproducible model to examine the downstream effects of gene loss, elucidating pathways that may be critical in development and disease processes.

The scientific importance of C15orf48 gene knockout cell lines cannot be overstated. They offer a unique opportunity for basic research as well as translational applications, allowing for the dissection of gene function and the identification of potential therapeutic targets. In clinical settings, understanding the role of C15orf48 could lead to the development of novel strategies for disease intervention, particularly in cancer treatment where gene dysregulation is common.

Compared to traditional knockout methods, our C15orf48 gene knockout cell lines provide enhanced specificity and efficiency, minimizing off-target effects and ensuring that researchers spend less time troubleshooting experimental variables. These cell lines are pre-validated, ready for immediate use, and compatible with a variety of assays, making them an accessible choice for both seasoned researchers and newcomers.

In conclusion, investing in C15orf48 Gene Knockout Cell Lines signifies a commitment to advancing research through innovative tools. Our company, renowned for its expertise in genetic engineering and cellular biology, is dedicated to providing high-quality products that empower researchers and clinicians to unlock new scientific discoveries while accelerating the pace of biomedical research.

Please note that all services are for research use only. Not intended for any clinical use.

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