Gene: BZW2
Official Full Name: basic leucine zipper and W2 domains 2provided by HGNC
Gene Summary: Enables cadherin binding activity. Involved in regulation of translational initiation. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27283 | BZW2 Knockout cell line (HeLa) | Human | BZW2 | 1:3~1:6 | Negative | Online Inquiry |
KO27284 | BZW2 Knockout cell line (HCT 116) | Human | BZW2 | 1:2~1:4 | Negative | Online Inquiry |
KO27285 | BZW2 Knockout cell line (HEK293) | Human | BZW2 | 1:3~1:6 | Negative | Online Inquiry |
KO27286 | BZW2 Knockout cell line (A549) | Human | BZW2 | 1:3~1:4 | Negative | Online Inquiry |
BZW2 Gene Knockout Cell Lines are genetically engineered cell lines designed to disrupt the expression of the BZW2 gene, a critical component involved in cellular processes such as cell proliferation, differentiation, and metabolism. By employing CRISPR/Cas9 technology, these cell lines facilitate precise gene knockout, enabling researchers to investigate the functional role of BZW2 in various biological contexts. The targeted elimination of this gene allows for the elucidation of its contributions to disease mechanisms, particularly in cancer and metabolic disorders.
The primary mechanism behind the BZW2 Gene Knockout Cell Lines involves the introduction of double-strand breaks in the DNA at specific loci, followed by error-prone repair processes that lead to insertions and deletions. This results in frameshifts or premature stop codons, effectively silencing the gene's expression. Researchers utilize these cell lines to assess changes in cellular behavior, signaling pathways, and phenotypic outcomes, providing valuable insights into the gene's function and potential as a therapeutic target.
In clinical and research settings, BZW2 knockouts have significant implications for drug development, gene therapy, and understanding pathophysiological processes. The ability to study the effects of BZW2 in a controlled environment helps identify novel biomarkers and therapeutic strategies, particularly in cancer research, where aberrant gene expression often plays a crucial role.
One of the primary advantages of our BZW2 Gene Knockout Cell Lines is their validated performance and reproducibility across multiple experiments. Unlike off-the-shelf alternatives, our cell lines come with extensive documentation and experimental protocols, allowing for seamless integration into existing research workflows. Furthermore, these cell lines are derived from well-characterized parental lines, ensuring consistency and reliability in experimental outcomes.
For researchers and clinicians seeking to deepen their understanding of gene function and disease mechanisms, the BZW2 Gene Knockout Cell Lines offer a robust platform for exploration and discovery. The strategic use of these cell lines can accelerate the translation of basic research findings into potential clinical applications.
Our company is committed to advancing scientific research through high-quality, customizable biological products that empower researchers to unlock new insights into genetic regulation and therapeutic interventions.
Please note that all services are for research use only. Not intended for any clinical use.
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