Gene: BTG1
Official Full Name: BTG anti-proliferation factor 1provided by HGNC
Gene Summary: This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia. [provided by RefSeq, Oct 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO38765 | BTG1 Knockout cell line (HeLa) | Human | BTG1 | 1:3~1:6 | Negative | Online Inquiry |
KO38766 | BTG1 Knockout cell line (HCT 116) | Human | BTG1 | 1:2~1:4 | Negative | Online Inquiry |
KO38767 | BTG1 Knockout cell line (HEK293) | Human | BTG1 | 1:3~1:6 | Negative | Online Inquiry |
KO38768 | BTG1 Knockout cell line (A549) | Human | BTG1 | 1:3~1:4 | Negative | Online Inquiry |
BTG1 Gene Knockout Cell Lines are specially engineered cellular models designed to facilitate the exploration of the BTG1 gene's role in various biological processes, particularly its involvement in cell proliferation, differentiation, and response to stress. By implementing CRISPR/Cas9 gene-editing technology, these cell lines exhibit a complete knock-out of the BTG1 gene, allowing researchers to study the functional consequences of its absence in a controlled environment.
The key function of BTG1 is its regulation of cell cycle progression and apoptosis, making it significant for understanding tumorigenesis and other diseases characterized by dysregulated cell growth. The knockout of BTG1 in these cell lines creates a valuable tool for researchers investigating the gene's contribution to cancer biology, immune responses, and cellular senescence, broadening the scope for potential therapeutic interventions.
In clinical and research settings, these knockout cell lines are particularly valuable for discovering novel biomarkers and therapeutic targets. They enable the evaluation of drug effects and the molecular mechanisms behind tumor behavior in a more precise manner. Unlike traditional methods that often rely on overexpression or silencing techniques, the BTG1 Gene Knockout Cell Lines provide a clean and definitive approach to studying gene function, mitigating the risk of off-target effects.
The unique selling point of our BTG1 Gene Knockout Cell Lines lies in their high specificity and reliability, along with the comprehensive background provided through our stringent validation processes. This ensures that researchers can trust that observed results stem directly from the knock-out of the BTG1 gene. Furthermore, these cell lines are readily adaptable for high-throughput screening applications.
The value of BTG1 Gene Knockout Cell Lines extends beyond academic use; they provide clinicians with insights that could lead to more effective therapies and personalized medicine strategies. Our commitment to quality and innovation in biotechnological advancements ensures that customers receive superior products backed by expert support and reliable performance. With years of experience in developing cutting-edge biological products, our company is dedicated to supporting the scientific community in uncovering the complexities of gene function and regulation.
Please note that all services are for research use only. Not intended for any clinical use.
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