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BRSK1 Knockout Cell Lines

Gene: BRSK1

Official Full Name: BR serine/threonine kinase 1provided by HGNC

Gene Summary: Enables magnesium ion binding activity and tau-protein kinase activity. Involved in mitotic G2 DNA damage checkpoint signaling and protein phosphorylation. Acts upstream of or within G2/M transition of mitotic cell cycle; peptidyl-serine phosphorylation; and response to UV. Located in cell junction; cytoplasm; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO06629 BRSK1 Knockout cell line (HeLa) Human BRSK1 1:3~1:6 Negative Online Inquiry
KO06630 BRSK1 Knockout cell line (HCT 116) Human BRSK1 1:2~1:4 Negative Online Inquiry
KO06631 BRSK1 Knockout cell line (HEK293) Human BRSK1 1:3~1:6 Negative Online Inquiry
KO06632 BRSK1 Knockout cell line (A549) Human BRSK1 1:3~1:4 Negative Online Inquiry

Background

BRSK1 Gene Knockout Cell Lines are genetically engineered cell lines designed to facilitate the in-depth study of the BRSK1 gene, an essential player in cellular processes including cell cycle regulation, differentiation, and metabolic signaling. These knockout models provide valuable insights into the biological ramifications of the absence of BRSK1, allowing researchers to explore its role in various physiological and pathological contexts, such as cancer and neurological disorders.

The primary function of BRSK1 Gene Knockout Cell Lines lies in their ability to enable precise investigations into the pathways regulated by BRSK1, leveraging CRISPR-Cas9 technology to induce targeted mutations that disrupt the gene's expression. Through this mechanism, researchers can assess the cellular behavior in the absence of functional BRSK1, evaluating changes in protein expression, signaling cascades, and overall cell viability, leading to a comprehensive understanding of its biological contributions.

In scientific research and clinical applications, these cell lines are crucial tools for elucidating the underlying mechanisms of diseases associated with BRSK1 dysregulation. They serve as platforms for drug discovery, enabling the testing of therapeutics aimed at restoring normal cell function or studying the effects of novel compounds specifically targeting BRSK1-related pathways.

What sets BRSK1 Gene Knockout Cell Lines apart from alternative models is their well-characterized genetic modifications verified by sequencing, ensuring reliability and reproducibility in experimental results. This precision allows for enhanced experimental design and data interpretation, making it an indispensable resource for both academic and pharmaceutical research settings.

Researchers and clinicians will find BRSK1 Gene Knockout Cell Lines invaluable for their ability to provide a clearer understanding of disease mechanisms, paving the way for new therapeutic strategies. Their unique advantages empower scientists to advance knowledge and drive innovations in targeted therapies effectively.

With a strong background in genetic engineering and molecular biology, our company prides itself on delivering high-quality biological products that push the boundaries of scientific inquiry. We are committed to supporting researchers in their quest for discovery and innovation by providing exceptional tools like BRSK1 Gene Knockout Cell Lines.

Please note that all services are for research use only. Not intended for any clinical use.

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