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BRPF3 Knockout Cell Lines

Gene: BRPF3

Official Full Name: bromodomain and PHD finger containing 3provided by HGNC

Gene Summary: Contributes to histone acetyltransferase activity. Involved in positive regulation of DNA replication. Located in nucleus. Part of MOZ/MORF histone acetyltransferase complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27785 BRPF3 Knockout cell line (HeLa) Human BRPF3 1:3~1:6 Negative Online Inquiry
KO27786 BRPF3 Knockout cell line (HCT 116) Human BRPF3 1:2~1:4 Negative Online Inquiry
KO27787 BRPF3 Knockout cell line (HEK293) Human BRPF3 1:3~1:6 Negative Online Inquiry
KO27788 BRPF3 Knockout cell line (A549) Human BRPF3 1:3~1:4 Negative Online Inquiry

Background

BRPF3 Gene Knockout Cell Lines are genetically engineered cell lines where the BRPF3 gene has been intentionally disrupted or eliminated through targeted genome-editing techniques. These cell lines serve as an essential tool for researchers investigating the functions of the BRPF3 protein, which is implicated in various cellular processes, including chromatin remodeling, gene expression regulation, and protein-protein interactions.

The key function of BRPF3 Gene Knockout Cell Lines is to provide a controlled environment to assess the phenotypic consequences of BRPF3 loss. By employing methodologies such as CRISPR-Cas9 or TALENs for gene editing, these cell lines allow for precise manipulation of the genetic material, enabling researchers to uncover the downstream effects of BRPF3 absence on cellular signaling pathways, differentiation, and metabolic activities. Furthermore, these cell lines can facilitate the study of disease models, particularly in cancer and neurodegenerative disorders, where aberrant gene regulation plays a crucial role.

The scientific importance of BRPF3 Gene Knockout Cell Lines extends to both basic and applied research contexts. Their applications are broad, including the study of epigenetic regulation, drug response, and cellular stress responses. In clinical settings, they hold the potential to aid in biomarker discovery and therapeutic target validation, thus contributing to personalized medicine approaches.

What sets BRPF3 Gene Knockout Cell Lines apart from alternative models is their specificity and the reliability of gene disruption, providing researchers with high fidelity in studying the BRPF3 gene's functional implications. The unique validity of these cell lines offers researchers a robust model system that mirrors pathological conditions more accurately than traditional methods, thereby enhancing the translational potential of their findings.

In a rapidly advancing field where precision and accuracy are paramount, BRPF3 Gene Knockout Cell Lines represent a valuable asset for scientists and clinicians alike. Our company’s expertise in gene editing and cell line development ensures that we provide cutting-edge products that meet the highest standards, fostering innovation and discovery in biological research.

Please note that all services are for research use only. Not intended for any clinical use.

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