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BRI3BP Knockout Cell Lines

Gene: BRI3BP

Official Full Name: BRI3 binding proteinprovided by HGNC

Gene Summary: Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25564 BRI3BP Knockout cell line (HeLa) Human BRI3BP 1:3~1:6 Negative Online Inquiry
KO25565 BRI3BP Knockout cell line (HCT 116) Human BRI3BP 1:2~1:4 Negative Online Inquiry
KO25566 BRI3BP Knockout cell line (HEK293) Human BRI3BP 1:3~1:6 Negative Online Inquiry
KO25567 BRI3BP Knockout cell line (A549) Human BRI3BP 1:3~1:4 Negative Online Inquiry

Background

BRI3BP Gene Knockout Cell Lines are advanced biological tools specifically engineered to study the functional implications of the BRI3BP gene in various cellular contexts. By employing CRISPR-Cas9 technology, these cell lines enable precise gene editing that results in the complete knockout of the BRI3BP gene, allowing researchers to assess its role in critical biological processes, including cellular stress response and apoptosis. The mechanistic approach to creating these cell lines involves the targeted introduction of double-strand breaks at the BRI3BP locus, followed by non-homologous end joining, which generates frameshift mutations effectively disrupting gene expression.

The scientific value of BRI3BP Gene Knockout Cell Lines is profound, as they serve as an indispensable resource in both basic and applied biomedical research. In clinical settings, understanding the functions of BRI3BP can shed light on its potential involvement in various diseases, including neurodegenerative disorders and cancer. These knockout models facilitate drug discovery and development by allowing for the screening of therapeutic compounds that may target the pathways influenced by BRI3BP, ultimately leading to innovative treatment options.

What sets our BRI3BP Gene Knockout Cell Lines apart from alternative products is the high efficiency of gene editing and the robust characterization accompanying each cell line. Our commitment to quality ensures that the genetic modifications are validated through comprehensive sequencing and functional assays. As a result, researchers can confidently utilize these cell lines for reproducible and significant findings.

The value of BRI3BP Gene Knockout Cell Lines lies in their ability to provide clearer insights into gene function, enhancing the potential for breakthroughs in treatment strategies for complex diseases. Our company prides itself on delivering high-quality biological products and resources, underpinned by extensive expertise in gene editing technologies and a dedication to supporting the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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