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BRI3 Knockout Cell Lines

Gene: BRI3

Official Full Name: brain protein I3provided by HGNC

Gene Summary: Enables identical protein binding activity. Predicted to be located in azurophil granule membrane and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28817 BRI3 Knockout cell line (HeLa) Human BRI3 1:3~1:6 Negative Online Inquiry
KO28818 BRI3 Knockout cell line (HCT 116) Human BRI3 1:2~1:4 Negative Online Inquiry
KO28819 BRI3 Knockout cell line (HEK293) Human BRI3 1:3~1:6 Negative Online Inquiry
KO28820 BRI3 Knockout cell line (A549) Human BRI3 1:3~1:4 Negative Online Inquiry

Background

BRI3 Gene Knockout Cell Lines are precisely engineered cellular models that have had the BRI3 gene selectively disrupted, allowing researchers to investigate the gene's role in various biological processes and disease states. The BRI3 gene encodes a protein that is associated with important cellular functions, including neurotransmission and cellular signaling pathways. By utilizing these knockout cell lines, scientists can effectively study the absence of BRI3 protein and its impact on cellular behavior, leading to a deeper understanding of neurodegenerative diseases and other conditions where BRI3 is implicated.

These cell lines function by employing CRISPR-Cas9 technology, ensuring high specificity and efficiency in gene editing. This method allows for the creation of stable knockout models, which are essential for long-term studies and the assessment of gene function. In a research setting, the BRI3 knockout cell lines facilitate investigations into mechanisms of action, enabling the development of targeted therapies and the exploration of novel drug compounds.

Scientifically, the availability of BRI3 gene knockout cell lines is critical for elucidating the roles of genes in health and disease. Their importance is underscored in both academic research and clinical applications, where understanding the underlying genetics can inform treatment strategies. Compared to alternative models, BRI3 knockout cell lines offer unparalleled precision for investigating gene function in a controlled environment, thus providing a more straightforward pathway to translate basic research findings into clinical insights.

For researchers and clinicians, the value of BRI3 gene knockout cell lines lies in their robust performance and reliability in experimental assays. These tools accelerate the pace of discovery, potentially leading to breakthroughs in therapeutic interventions for neurodegenerative and psychiatric disorders. Our company specializes in developing high-quality genetic models, ensuring researchers have access to innovative products that enhance their research capabilities and drive scientific advancement.

Please note that all services are for research use only. Not intended for any clinical use.

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