Gene: BPHL
Official Full Name: biphenyl hydrolase likeprovided by HGNC
Gene Summary: This gene encodes a member of the serine protease family of hydrolytic enzymes which contain a serine in their active site. The encoded protein may play a role in activation of the antiviral prodrug valacyclovir. Alternatively spliced transcript variants have been described.[provided by RefSeq, Jan 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO38785 | BPHL Knockout cell line (HeLa) | Human | BPHL | 1:3~1:6 | Negative | Online Inquiry |
KO38786 | BPHL Knockout cell line (HCT 116) | Human | BPHL | 1:2~1:4 | Negative | Online Inquiry |
KO38787 | BPHL Knockout cell line (HEK293) | Human | BPHL | 1:3~1:6 | Negative | Online Inquiry |
KO38788 | BPHL Knockout cell line (A549) | Human | BPHL | 1:3~1:4 | Negative | Online Inquiry |
BPHL Gene Knockout Cell Lines are genetically modified cellular models specifically designed to study the biological functions of the BPHL gene (butyrylcholinesterase-like protein) by creating a functional knockout environment. This product serves as a vital tool for researchers investigating the gene's role in various physiological processes, including its involvement in neurodegenerative diseases, metabolic pathways, and pharmacogenomics.
The primary function of these knockout cell lines is to eliminate the expression of the BPHL gene, allowing scientists to assess the resultant phenotypic variations compared to wild-type cells. The knockout is achieved through advanced genome editing technologies such as CRISPR/Cas9, which enable precise alterations at the genomic level. This targeted approach harnesses the natural DNA repair mechanisms of cells, resulting in a robust and reproducible loss of gene function.
The scientific significance of BPHL Gene Knockout Cell Lines is profound within both research and clinical settings. They facilitate the exploration of gene function, the understanding of disease mechanisms, and the identification of potential therapeutic targets. Furthermore, these cell lines can be employed in drug discovery processes, aiding in the development of tailored therapies based on genetic profiles.
What sets our BPHL Gene Knockout Cell Lines apart from alternative products is our commitment to quality and validation. Each cell line undergoes rigorous testing to ensure complete knockout of the target gene, alongside comprehensive characterization to confirm stability and viability. Researchers can rely on these models to produce reproducible results, ultimately enhancing the reliability of their findings.
The value of this product lies in its ability to provide clear insights into gene function and therapeutic implications, thus meeting the evolving needs of researchers and clinicians alike. By leveraging these advanced models, users can significantly accelerate their scientific discoveries and contribute to the advancement of precision medicine.
Our company, with extensive expertise in genetic engineering and cell biology, prides itself on delivering high-quality biological products backed by thorough scientific validation. We are committed to supporting the research community with innovative tools designed to further the understanding of complex biological processes.
Please note that all services are for research use only. Not intended for any clinical use.
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