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BORCS6 Knockout Cell Lines

Gene: BORCS6

Official Full Name: BLOC-1 related complex subunit 6provided by HGNC

Gene Summary: Enables identical protein binding activity. Involved in lysosome localization. Part of BORC complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO19386 BORCS6 Knockout cell line (HeLa) Human BORCS6 1:3~1:6 Negative Online Inquiry
KO19387 BORCS6 Knockout cell line (HCT 116) Human BORCS6 1:2~1:4 Negative Online Inquiry
KO19388 BORCS6 Knockout cell line (HEK293) Human BORCS6 1:3~1:6 Negative Online Inquiry
KO19389 BORCS6 Knockout cell line (A549) Human BORCS6 1:3~1:4 Negative Online Inquiry

Background

BORCS6 Gene Knockout Cell Lines are a specialized model system developed to facilitate the study of BORCS6 (BLOC-1-related complex subunit 6), a critical protein involved in intracellular trafficking and organelle biogenesis. By employing CRISPR-Cas9 technology, these cell lines have been engineered to specifically disrupt the BORCS6 gene, allowing researchers to investigate the downstream effects on cellular processes and mitochondrial function.

The primary function of BORCS6 involves its role in the biogenesis of lysosomes and endosomes, as well as its regulatory influence on cargo transport and membrane dynamics. In the absence of functional BORCS6, these knockout cell lines exhibit distinctive morphological and functional alterations that can serve as a basis for understanding various pathophysiological conditions, such as neurodegenerative diseases and metabolic disorders.

From a scientific standpoint, BORCS6 gene knockout cell lines hold immense importance in both basic and applied research settings. They provide a robust platform for elucidating the mechanisms by which aberrations in intracellular trafficking can lead to disease. These models are invaluable for drug discovery and testing therapeutic strategies aimed at restoring normal cellular function or mitigating the effects of BORCS6-related diseases.

Unique to our offering, these cell lines are rigorously characterized and undergo extensive validation to ensure reproducibility and reliability, making them superior to similar products on the market. Additionally, our commitment to providing detailed technical support and comprehensive documentation enhances the user experience, equipping researchers with the necessary tools for successful experimentation.

For researchers and clinicians focused on cell biology, neurobiology, and metabolic disorders, BORCS6 Gene Knockout Cell Lines represent a vital asset that can accelerate research progress and innovations in therapeutic interventions. Our company prides itself on delivering high-quality biological products that empower the scientific community, backed by a team of experts dedicated to advancing research capabilities.

Please note that all services are for research use only. Not intended for any clinical use.

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