Gene: BLOC1S4
Official Full Name: biogenesis of lysosomal organelles complex 1 subunit 4provided by HGNC
Gene Summary: This intronless gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and is a model for Hermansky-Pudlak syndrome. The encoded protein may play a role in intracellular vesicular trafficking. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19430 | BLOC1S4 Knockout cell line (HeLa) | Human | BLOC1S4 | 1:3~1:6 | Negative | Online Inquiry |
KO19431 | BLOC1S4 Knockout cell line (HCT 116) | Human | BLOC1S4 | 1:2~1:4 | Negative | Online Inquiry |
KO19432 | BLOC1S4 Knockout cell line (HEK293) | Human | BLOC1S4 | 1:3~1:6 | Negative | Online Inquiry |
KO19433 | BLOC1S4 Knockout cell line (A549) | Human | BLOC1S4 | 1:3~1:4 | Negative | Online Inquiry |
BLOC1S4 Gene Knockout Cell Lines are genetically modified cell lines specifically engineered to disrupt the expression of the BLOC1S4 gene, facilitating in-depth studies of its biological role and associated pathways. These cell lines utilize CRISPR-Cas9 technology to achieve precise gene knockout, enabling researchers to observe the resultant phenotypic variations and understand the functional implications of BLOC1S4 in cellular processes.
The primary function of BLOC1S4 is linked to its involvement in the biogenesis of lysosome-related organelles, playing a critical role in cellular signaling, metalloprotein function, and pigmentation processes. By generating knockout cell lines, researchers can explore these pathways and unravel the complex mechanisms implicated in various conditions such as Hermansky-Pudlak syndrome or other disorders related to lysosomal function. The manipulation of this gene allows for the elucidation of its role in intracellular trafficking and its connection to cellular homeostasis, providing insights essential for therapeutic development.
The scientific importance of BLOC1S4 Gene Knockout Cell Lines extends to both research and clinical applications. In research environments, they serve as a fundamental tool for dissecting the molecular underpinnings of cellular dysfunctions and contribute to drug discovery initiatives by enabling high-throughput screening of potential therapeutic agents. Clinicians can leverage findings from these studies to inform genetic counseling and potential treatment options for patients with related disorders.
One of the key advantages of our BLOC1S4 Gene Knockout Cell Lines over competitor products is their high specificity and efficiency in gene disruption, ensuring reproducibility and reliable outcomes. Moreover, all cell lines come with extensive documentation detailing their characterization and experimental validation, which is crucial for meeting regulatory compliance and enhancing research integrity.
For researchers, clinicians, and pharmaceutical companies, utilizing BLOC1S4 Gene Knockout Cell Lines can significantly enhance the quality of research findings and therapeutic strategies. Our commitment to providing high-quality biological products, underpinned by rigorous scientific methodologies, underscores our expertise and leadership in the field, ensuring that customers can depend on us for cutting-edge research tools that drive innovation and discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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