Gene: BIRC6
Official Full Name: baculoviral IAP repeat containing 6provided by HGNC
Gene Summary: This gene encodes a protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain. This protein inhibits apoptosis by facilitating the degradation of apoptotic proteins by ubiquitination. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20428 | BIRC6 Knockout cell line (HeLa) | Human | BIRC6 | 1:3~1:6 | Negative | Online Inquiry |
KO20429 | BIRC6 Knockout cell line (HCT 116) | Human | BIRC6 | 1:2~1:4 | Negative | Online Inquiry |
KO20430 | BIRC6 Knockout cell line (HEK293) | Human | BIRC6 | 1:3~1:6 | Negative | Online Inquiry |
KO20431 | BIRC6 Knockout cell line (A549) | Human | BIRC6 | 1:3~1:4 | Negative | Online Inquiry |
BIRC6 Gene Knockout Cell Lines are meticulously developed cell lines that have undergone genetic modification to ablate the expression of the BIRC6 gene. BIRC6, known for its role in apoptosis regulation and cell survival, encodes a member of the inhibitor of apoptosis protein (IAP) family. These knockout cell lines serve as crucial tools for researchers investigating the intrinsic cellular pathways of apoptosis, immune evasion, and cancer biology.
Functionally, the BIRC6 gene plays a significant role in inhibiting programmed cell death, thereby contributing to cellular resilience under stress conditions. By utilizing BIRC6 Gene Knockout Cell Lines, researchers can elucidate the downstream effects of BIRC6 loss on apoptosis-related signaling pathways and better understand the gene's implications in malignancies and therapeutic resistance. The ablation of this gene allows for enhanced examination of how cancer cells manipulate apoptotic mechanisms to survive and proliferate, making these models particularly valuable in drug discovery and development.
The scientific importance of BIRC6 Gene Knockout Cell Lines extends to applications in both basic and translational research. They provide a robust framework for studying cancer therapies that target prosurvival signals, thus facilitating the identification of potential biomarkers for treatment response. Furthermore, these cell lines can be instrumental in developing innovative strategies to combat treatment-resistant cancers.
What sets BIRC6 Gene Knockout Cell Lines apart from other cell models is their precision and reliability, backed by extensive validation studies. They offer researchers a unique advantage in obtaining reproducible data while navigating the complexity of apoptotic pathways. This specificity ensures accurate interpretation of results, enhancing confidence in experimental outcomes.
For researchers and clinicians focused on advancing cancer therapies and understanding cell survival mechanisms, BIRC6 Gene Knockout Cell Lines represent a vital resource. Our commitment to providing high-quality biological tools is reinforced by our extensive experience in the field, ensuring that our products are supported by sound scientific principles and advanced methodologies. By choosing our BIRC6 Gene Knockout Cell Lines, users gain access to unparalleled quality and expertise, driving innovation in their research initiatives.
Please note that all services are for research use only. Not intended for any clinical use.
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