Gene: BICRA
Official Full Name: BRD4 interacting chromatin remodeling complex associated proteinprovided by HGNC
Gene Summary: Enables transcription regulator activator activity. Involved in positive regulation of DNA-templated transcription. Located in nucleus. Part of SWI/SNF complex. Implicated in Coffin-Siris syndrome 12. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO06468 | BICRA Knockout cell line (HeLa) | Human | BICRA | 1:3~1:6 | Negative | Online Inquiry |
KO06469 | BICRA Knockout cell line (HCT 116) | Human | BICRA | 1:2~1:4 | Negative | Online Inquiry |
KO06470 | BICRA Knockout cell line (HEK293) | Human | BICRA | 1:3~1:6 | Negative | Online Inquiry |
KO06471 | BICRA Knockout cell line (A549) | Human | BICRA | 1:3~1:4 | Negative | Online Inquiry |
BICRA Gene Knockout Cell Lines are advanced, engineered cellular models designed to facilitate the study of the BICRA gene, a critical player in various biological processes, including cellular response to stress and gene regulation. These cell lines are created using cutting-edge CRISPR/Cas9 technology, which enables precise modifications in the genome, thereby allowing researchers to create specific knockout mutations that effectively eliminate the expression of the BICRA gene. This targeted approach provides a reliable platform for investigating the gene’s role in both normal physiology and pathological conditions.
The key function of BICRA Gene Knockout Cell Lines lies in their ability to serve as a vital tool for elucidating the biological functions of the BICRA gene. By comparing phenotypic and molecular characteristics of knockout cells to wild-type cells, researchers can gain insights into the gene’s involvement in processes like apoptosis, cell cycle regulation, and responses to environmental stressors. Additionally, these cell lines can be integrated into drug discovery pipelines, allowing for the assessment of therapeutic candidates aimed at modulating BICRA function or compensating for its loss.
In research and clinical settings, BICRA Gene Knockout Cell Lines are invaluable for advancing our understanding of gene dysregulation in diseases such as cancer and metabolic disorders. They represent an essential resource for pharmacological studies and the development of gene-targeted therapies.
What sets BICRA Gene Knockout Cell Lines apart from conventional models is their high specificity and reproducibility, significantly reducing variability and bias in experimental outcomes. Furthermore, the accessibility of the CRISPR/Cas9 gene-editing technology offers researchers a straightforward pathway to gene knockout experiments, reducing time and resources spent on generating models.
Investing in BICRA Gene Knockout Cell Lines translates to enhanced precision and reliability in experimental design for researchers and clinicians alike. With our extensive portfolio of state-of-the-art biological products and a commitment to quality and innovation, our company stands at the forefront of delivering robust solutions to the scientific community, empowering investigations that drive discoveries and advance therapeutic strategies.
Please note that all services are for research use only. Not intended for any clinical use.
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