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BHLHA15 Knockout Cell Lines

Gene: BHLHA15

Official Full Name: basic helix-loop-helix family member a15provided by HGNC

Gene Summary: Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in several processes, including cellular response to glucose starvation; negative regulation of myotube differentiation; and neuron differentiation. Predicted to act upstream of or within several processes, including cell-cell adhesion mediated by cadherin; intracellular distribution of mitochondria; and type B pancreatic cell maturation. Predicted to be located in chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO19449 BHLHA15 Knockout cell line (HeLa) Human BHLHA15 1:3~1:6 Negative Online Inquiry
KO19450 BHLHA15 Knockout cell line (HCT 116) Human BHLHA15 1:2~1:4 Negative Online Inquiry
KO19451 BHLHA15 Knockout cell line (HEK293) Human BHLHA15 1:3~1:6 Negative Online Inquiry

Background

BHLHA15 Gene Knockout Cell Lines represent a pivotal innovation in the field of genetic research and cellular biology, specifically designed to facilitate the investigation of the BHLHA15 gene's role in various biological processes. These genetically modified cell lines are created through targeted gene disruption, effectively inactivating or knocking out the BHLHA15 gene. This provides a unique experimental tool for researchers aiming to elucidate the gene's function in pathways related to cellular differentiation, metabolism, and response to external stimuli.

The primary mechanism by which these knockout cell lines operate is by eliminating the gene's expression, thereby allowing for direct observation of phenotypic changes and molecular variations influenced by the absence of BHLHA15. This is especially instrumental in studying diseases where this gene may play a significant role, including certain cancers and metabolic disorders. Researchers can utilize these cell lines to perform a range of assays, including gene expression profiling, metabolic analysis, and drug response testing, unlocking insight into the gene's biological significance.

The scientific importance of BHLHA15 Gene Knockout Cell Lines extends to both fundamental research and clinical applications. In laboratory settings, these cell lines can be leveraged to better understand cellular mechanisms and identify potential therapeutic targets. Clinicians may find these models invaluable in drug discovery processes, particularly when assessing the efficacy of new treatments aimed at modulating the gene's function.

What sets BHLHA15 Gene Knockout Cell Lines apart from alternative models is their precise gene targeting, which minimizes off-target effects that can confound experimental results. Additionally, these cell lines are rigorously validated, ensuring reliable results and reproducibility—critical factors for researchers striving for credibility in their findings.

Ultimately, investing in BHLHA15 Gene Knockout Cell Lines equips researchers and clinicians with an advanced tool to deepen their understanding of cellular pathways and disease mechanisms. Our company is committed to advancing scientific progress, providing high-quality genetic models tailored to meet the demanding needs of the research community. With our expertise in genetic engineering and cell line development, you can trust that our products are at the forefront of innovation, ensuring your research reaches its fullest potential.

Please note that all services are for research use only. Not intended for any clinical use.

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