Gene: BEND3
Official Full Name: BEN domain containing 3provided by HGNC
Gene Summary: Enables rDNA binding activity. Involved in negative regulation of macromolecule biosynthetic process; positive regulation of ATP metabolic process; and protein homooligomerization. Located in heterochromatin; nucleolus; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19452 | BEND3 Knockout cell line (HeLa) | Human | BEND3 | 1:3~1:6 | Negative | Online Inquiry |
KO19453 | BEND3 Knockout cell line (HCT 116) | Human | BEND3 | 1:2~1:4 | Negative | Online Inquiry |
KO19454 | BEND3 Knockout cell line (HEK293) | Human | BEND3 | 1:3~1:6 | Negative | Online Inquiry |
KO19455 | BEND3 Knockout cell line (A549) | Human | BEND3 | 1:3~1:4 | Negative | Online Inquiry |
BEND3 Gene Knockout Cell Lines are engineered cell lines specifically designed to selectively inactivate the BEND3 gene, which encodes a protein implicated in cellular processes such as transcription regulation and chromatin remodeling. These knockout cell lines are pivotal tools in molecular and cellular biology, enabling researchers to investigate the functional role of the BEND3 gene in various biological contexts.
The key function of these cell lines lies in their ability to provide insights into the consequences of BEND3 gene loss. Using CRISPR-Cas9 technology, the BEND3 knockout is achieved with high specificity, allowing for precise studies of gene function. By observing changes in cellular behavior, signaling pathways, and gene expression profiles in these knockout lines, researchers can uncover the gene's role in cell proliferation, differentiation, and potential links to diseases, particularly cancers and metabolic disorders.
In clinical and research settings, BEND3 Gene Knockout Cell Lines serve as valuable models for various applications, including drug development, gene therapy research, and understanding genetic contributions to disease. The ability to study the effects of BEND3 loss provides a clearer understanding of its implications in pathological contexts, thus aiding in the identification of therapeutic targets.
What sets our BEND3 Gene Knockout Cell Lines apart from alternatives is the rigorous validation process that ensures effective and stable knockout characteristics. They are generated under strict quality controls, ensuring reproducibility and reliability in experimental outcomes, which is crucial for experimental integrity. Additionally, our cell lines come with detailed characterization data, facilitating their immediate use in experiments without the need for additional optimization.
For researchers and clinicians, the BEND3 Gene Knockout Cell Lines represent an essential resource that bridges basic research and translational science. By choosing our product, users gain access to a high-quality tool that not only accelerates their research but also enhances the potential for groundbreaking discoveries related to gene function and disease mechanisms.
With years of expertise in the field of genetic engineering and cellular biology, our company stands at the forefront of innovative biological product offerings, committed to supporting scientists in their quest for knowledge and discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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