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BCORL1 Knockout Cell Lines

Gene: BCORL1

Official Full Name: BCL6 corepressor like 1provided by HGNC

Gene Summary: The protein encoded by this gene is a transcriptional corepressor that is found tethered to promoter regions by DNA-binding proteins. The encoded protein can interact with several different class II histone deacetylases to repress transcription. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO20841 BCORL1 Knockout cell line (HeLa) Human BCORL1 1:3~1:6 Negative Online Inquiry
KO20842 BCORL1 Knockout cell line (HCT 116) Human BCORL1 1:2~1:4 Negative Online Inquiry
KO20843 BCORL1 Knockout cell line (HEK293) Human BCORL1 1:3~1:6 Negative Online Inquiry
KO20844 BCORL1 Knockout cell line (A549) Human BCORL1 1:3~1:4 Negative Online Inquiry

Background

BCORL1 Gene Knockout Cell Lines are specialized cell lines that have been genetically engineered to have a complete knockout of the BCORL1 gene, a critical regulator of gene expression associated with various biological processes and disease states. These cell lines are invaluable tools for researchers investigating the role of BCORL1 in cellular development, differentiation, and oncogenesis.

The mechanism by which these cell lines function revolves around the loss of BCORL1 expression, which allows for the study of downstream effects and signaling pathways that are impacted by its absence. By utilizing CRISPR/Cas9 technology or other gene-editing methods to disrupt the BCORL1 gene, these cell lines provide a robust platform for examining changes in gene expression profiles, cellular behavior, and pathophysiological mechanisms in both normal and pathological states.

The scientific importance of BCORL1 Gene Knockout Cell Lines lies in their applications within both basic research and clinical settings. These models can be employed to investigate diseases such as cancer, where the dysregulation of gene expression plays a crucial role. Additionally, they offer a unique opportunity to test potential therapeutic interventions aimed at restoring normal cellular function that may be disrupted by the loss of BCORL1.

What sets these knockout cell lines apart from alternatives on the market is their precision and reliability. Each cell line undergoes rigorous validation to confirm the complete knockout of the BCORL1 gene, ensuring that researchers can obtain reproducible data that accurately reflects the biological consequences of gene loss. Moreover, the availability of these well-characterized models saves time and resources, enabling researchers to focus on their experiments rather than developing their own knockouts.

For researchers, clinicians, and pharmaceutical companies, the BCORL1 Gene Knockout Cell Lines offer unmatched value in their ability to advance our understanding of gene function and disease mechanisms. By utilizing these cell lines, you not only gain insights into critical biological processes but also contribute to the potential development of innovative treatment strategies.

As a leader in biotechnology, our company is committed to providing high-quality biological tools that empower the scientific community. We take pride in our expertise and our ability to support groundbreaking research efforts with reliable and precise biological products like the BCORL1 Gene Knockout Cell Lines.

Please note that all services are for research use only. Not intended for any clinical use.

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