Gene: BBOF1
Official Full Name: basal body orientation factor 1provided by HGNC
Gene Summary: Predicted to be involved in sperm axoneme assembly. Predicted to act upstream of or within several processes, including cilium movement involved in cell motility; negative regulation of microtubule depolymerization; and protein stabilization. Predicted to be located in axoneme; ciliary basal body; and sperm flagellum. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26229 | BBOF1 Knockout cell line (HeLa) | Human | BBOF1 | 1:3~1:6 | Negative | Online Inquiry |
KO26230 | BBOF1 Knockout cell line (HCT 116) | Human | BBOF1 | 1:2~1:4 | Negative | Online Inquiry |
KO26231 | BBOF1 Knockout cell line (HEK293) | Human | BBOF1 | 1:3~1:6 | Negative | Online Inquiry |
KO26232 | BBOF1 Knockout cell line (A549) | Human | BBOF1 | 1:3~1:4 | Negative | Online Inquiry |
BBOF1 Gene Knockout Cell Lines are meticulously engineered cellular models generated through the precise deletion of the BBOF1 gene, offering researchers a powerful tool to investigate gene function, cellular mechanisms, and biological pathways associated with BBOF1. The knockout of this gene, known to play a critical role in various physiological processes, allows for the comprehensive study of its absence in cellular functions and disease states.
These cell lines operate on a robust CRISPR-Cas9 editing system, which enables accurate gene targeting, ensuring that the knockout is specific and efficient. By using these cell lines, scientists can elucidate the consequences of BBOF1 loss, providing insights into the gene's contribution to cellular behavior, regulation of cell cycle, and apoptosis. This knowledge is crucial for understanding its role in various health conditions, including cancer, metabolic disorders, and genetic diseases.
In research and clinical settings, BBOF1 Gene Knockout Cell Lines serve as vital models for drug discovery, toxicology screenings, and biomarker identification. They are instrumental in validating target pathways in human disease, thus bridging the gap between basic research and therapeutic development. The specificity of the knockout minimizes off-target effects often encountered with other gene editing techniques, enhancing the reliability of experimental outcomes.
One of the remarkable advantages of BBOF1 Gene Knockout Cell Lines is their capacity to offer reproducible and physiologically relevant data, which is indispensable for researchers seeking robust experimental frameworks. Unlike traditional cell lines that may yield variable data, these knockout lines provide a consistent background for studying gene function and interactions.
As an innovative company dedicated to advancing biomedical research, our expertise lies in producing high-quality biologically relevant tools such as BBOF1 Gene Knockout Cell Lines. We are committed to empowering researchers and clinicians with the best resources to facilitate scientific breakthroughs and improve health outcomes.
Please note that all services are for research use only. Not intended for any clinical use.
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