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BARX1 Knockout Cell Lines

Gene: BARX1

Official Full Name: BARX homeobox 1provided by HGNC

Gene Summary: This gene encodes a member of the Bar subclass of homeobox transcription factors. Studies of the mouse and chick homolog suggest the encoded protein may play a role in developing teeth and craniofacial mesenchyme of neural crest origin. The protein may also be associated with differentiation of stomach epithelia. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO19484 BARX1 Knockout cell line (HeLa) Human BARX1 1:3~1:6 Negative Online Inquiry
KO19485 BARX1 Knockout cell line (HEK293) Human BARX1 1:3~1:6 Negative Online Inquiry
KO19486 BARX1 Knockout cell line (A549) Human BARX1 1:3~1:4 Negative Online Inquiry

Background

BARX1 Gene Knockout Cell Lines are sophisticated biological tools designed for the study of the BARX1 gene, known for its role in dental and craniofacial development as well as implications in various cancers. These cell lines are generated by employing advanced CRISPR/Cas9 gene-editing technology, which specifically targets and disrupts the BARX1 gene, leading to its functional knockout. This precise alteration allows researchers to investigate the consequences of BARX1 loss on cellular behavior, signaling pathways, and developmental processes in a controlled experimental setting.

The primary function of the BARX1 Gene Knockout Cell Lines is to serve as a model system for elucidating the gene's role in development and disease. By creating a cellular environment devoid of BARX1, researchers can observe alterations in proliferation, differentiation, and apoptosis, thereby uncovering potential mechanisms underlying BARX1-associated pathologies. This gene knockout model is crucial for advancing our understanding of craniofacial anomalies and providing insights into cancer biology, particularly in tumors where BARX1 expression is altered.

What sets our BARX1 Gene Knockout Cell Lines apart from conventional knockout models is their high efficiency and specificity, guaranteed by the precision of CRISPR/Cas9 technology. Unlike earlier methods, which often resulted in off-target effects or incomplete knockouts, our product ensures a reliable and reproducible gene disruption, thereby enhancing the credibility of the experimental outcomes. This specificity is not only vital for academic research but also crucial for potential therapeutic applications, where understanding the precise functions of genes can inform the development of targeted interventions.

The value of BARX1 Gene Knockout Cell Lines in both research and clinical settings cannot be overstated. For researchers, these cell lines offer a unique opportunity to dissect the role of BARX1 in various physiological and pathological contexts, paving the way for novel therapeutic strategies. Clinicians could also benefit from insights gained through this research, as a better understanding of BARX1-related mechanisms could inform patient care approaches in genetic disorders and cancers.

Our company is committed to excellence in the field of genetic research and provides a robust portfolio of biological products, including our BARX1 Gene Knockout Cell Lines. With our focus on innovation and quality, we equip researchers and clinicians with the essential tools needed to advance scientific knowledge and improve patient outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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