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BAGE4 Knockout Cell Lines

Gene: BAGE4

Official Full Name: BAGE family member 4provided by HGNC

Gene Summary: Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24292 BAGE4 Knockout cell line (HeLa) Human BAGE4 1:3~1:6 Negative Online Inquiry
KO24293 BAGE4 Knockout cell line (HCT 116) Human BAGE4 1:2~1:4 Negative Online Inquiry
KO24294 BAGE4 Knockout cell line (HEK293) Human BAGE4 1:3~1:6 Negative Online Inquiry
KO24295 BAGE4 Knockout cell line (A549) Human BAGE4 1:3~1:4 Negative Online Inquiry

Background

BAGE4 Gene Knockout Cell Lines are specifically engineered cellular models designed to facilitate the study of BAGE4 (B melanoma antigen). These cell lines have undergone targeted gene editing techniques, such as CRISPR-Cas9, to create knockout variants that lack functional BAGE4 expression. This modification allows researchers to dissect the biological functions of BAGE4, including its role in tumor development and immune evasion, thus providing an essential tool for elucidating the mechanisms underlying various cancers.

The key function of BAGE4 Gene Knockout Cell Lines is to serve as a controlled environment for understanding how the absence of BAGE4 impacts cellular behavior. Utilizing these knockout models, researchers can assess vital processes, including cell proliferation, signaling pathways, and immune responses, thus offering significant insights into tumor biology and immunology. Such studies are crucial in identifying potential therapeutic targets and prognostic markers in cancer.

The scientific importance of these cell lines extends to both research and clinical applications. In the research arena, they enable the exploration of BAGE4 as a target for cancer immunotherapy, particularly since BAGE4 has been implicated in the modulation of T-cell responses. Clinically, understanding BAGE4's function may lead to enhanced patient stratification and innovative treatment strategies in oncology.

What sets BAGE4 Gene Knockout Cell Lines apart from alternative models is their high specificity and reliability. Unlike conventional cell lines that may retain partial functionality of the target gene, our knockout lines provide a true representation of the gene's absence, thereby yielding accurate experimental results. Furthermore, they are developed under stringent quality control measures, ensuring reproducible outcomes.

Researchers and clinicians will find these cell lines invaluable, as they simplify complex experimental designs and accelerate discoveries. The ability to study BAGE4 without confounding variables marks a significant advantage in translational research efforts aimed at improving patient outcomes.

Our company boasts a robust portfolio of genetically modified cell lines and a commitment to supporting innovative research. With expertise in cellular models, we stand ready to partner with the scientific community to push the boundaries of biological discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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