Gene: BAGE3
Official Full Name: BAGE family member 3provided by HGNC
Gene Summary: Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24288 | BAGE3 Knockout cell line (HeLa) | Human | BAGE3 | 1:3~1:6 | Negative | Online Inquiry |
KO24289 | BAGE3 Knockout cell line (HCT 116) | Human | BAGE3 | 1:2~1:4 | Negative | Online Inquiry |
KO24290 | BAGE3 Knockout cell line (HEK293) | Human | BAGE3 | 1:3~1:6 | Negative | Online Inquiry |
KO24291 | BAGE3 Knockout cell line (A549) | Human | BAGE3 | 1:3~1:4 | Negative | Online Inquiry |
BAGE3 Gene Knockout Cell Lines comprise a specialized set of engineered cell lines featuring targeted deletions of the BAGE3 gene, which is associated with various tumor types and plays a critical role in cancer immunology. These knockout cell lines are created using advanced CRISPR-Cas9 technology, ensuring a precise and effective gene editing process that disrupts the BAGE3 gene, facilitating the study of its function and role within cellular pathways.
The primary mechanism of action of the BAGE3 knockout cell lines lies in the complete ablation of the BAGE3 protein, allowing researchers to observe phenotypic changes and molecular alterations that occur in its absence. This enables an in-depth analysis of BAGE3's involvement in cancer progression, immune evasion, and potential therapeutic targets for immunotherapy. These cell lines serve as valuable tools in elucidating the mechanisms underlying tumorigenesis and in developing novel anti-cancer strategies.
In terms of scientific significance, BAGE3 gene knockout cell lines can be utilized in diverse applications, including drug screening, biomarker discovery, and functional assays in both in vitro and in vivo studies. Their role in elucidating tumor biology makes them a vital resource for researchers exploring cancer mechanisms or working in pharmaceutical development.
One of the standout advantages of our BAGE3 Knockout Cell Lines is their high specificity and reproducibility, ensuring consistent and reliable results across experiments, which is critical in research settings. Unlike standard cell lines, which may express variable levels of off-target genes, our precisely engineered lines guarantee an accurate assessment of BAGE3's biological function.
For researchers and clinicians aiming to delve into the complexities of cancer biology, utilizing BAGE3 knockout cell lines represents a significant step forward. Their ability to provide clear insights into the role of BAGE3 in tumor development and immune response is invaluable for developing future therapies.
At our company, we specialize in delivering high-quality biological products backed by extensive expertise in genetic engineering and molecular biology. Our commitment to innovation ensures that you have access to cutting-edge tools that propel your research and clinical endeavors, paving the way for breakthroughs in understanding and treating cancer.
Please note that all services are for research use only. Not intended for any clinical use.
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