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BAGE Knockout Cell Lines

Gene: BAGE

Official Full Name: B melanoma antigenprovided by HGNC

Gene Summary: This gene encodes a tumor antigen recognized by autologous cytolytic lymphocytes (CTL). [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO38861 BAGE Knockout cell line (HeLa) Human BAGE 1:3~1:6 Negative Online Inquiry
KO38862 BAGE Knockout cell line (HCT 116) Human BAGE 1:2~1:4 Negative Online Inquiry
KO38863 BAGE Knockout cell line (HEK293) Human BAGE 1:3~1:6 Negative Online Inquiry
KO38864 BAGE Knockout cell line (A549) Human BAGE 1:3~1:4 Negative Online Inquiry

Background

BAGE Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to lack the expression of the BAGE (B melanoma antigen) gene. This product is instrumental in elucidating the role of BAGE in tumor biology, immune response, and cancer progression. By utilizing CRISPR/Cas9 technology or similar gene-editing methodologies, these cell lines provide a powerful platform for researchers to explore the functional consequences of BAGE knockout in various biological contexts.

The primary function of BAGE Gene Knockout Cell Lines revolves around their ability to serve as a customizable model for studying cellular mechanics in both in vitro and in vivo settings. Researchers can utilize these lines to decipher the molecular pathways altered by the absence of BAGE, investigating how this impacts aspects such as cell proliferation, apoptosis, and immune evasion. This knowledge is particularly valuable in cancer research, where BAGE is often implicated in various malignancies, allowing for a deeper understanding of tumor microenvironments and potential therapeutic interventions.

The scientific importance of BAGE Gene Knockout Cell Lines extends to their applications not only in academic research but also in clinical settings. Their utility in drug discovery, particularly for immune-oncology therapies, allows for targeted investigations that can inform therapeutic strategies for patients. The specificity and reproducibility of results derived from these knockout models offer researchers assurance in their findings.

One key advantage of BAGE Gene Knockout Cell Lines over traditional models is their enhanced precision in gene targeting, minimizing off-target effects. Furthermore, these products provide researchers with ready-to-use, consistent, and well-characterized cell lines that are maintenance-friendly, eliminating the need for time-consuming transfection or traditional knockout techniques.

For researchers and clinicians alike, the value of BAGE Gene Knockout Cell Lines lies in their ability to advance our understanding of cancer mechanisms and foster the development of personalized medicine approaches. Their inherent design allows users to generate reliable, reproducible data that can significantly contribute to groundbreaking discoveries in cancer biology.

With years of expertise in genetic engineering and a commitment to delivering high-quality biological products, our company is dedicated to equipping scientists and clinicians with the tools necessary to push the boundaries of research and enhance patient care.

Please note that all services are for research use only. Not intended for any clinical use.

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