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AVL9 Knockout Cell Lines

Gene: AVL9

Official Full Name: AVL9 cell migration associatedprovided by HGNC

Gene Summary: Involved in cell migration. Located in recycling endosome. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29890 AVL9 Knockout cell line (HeLa) Human AVL9 1:3~1:6 Negative Online Inquiry
KO29891 AVL9 Knockout cell line (HCT 116) Human AVL9 1:2~1:4 Negative Online Inquiry
KO29892 AVL9 Knockout cell line (HEK293) Human AVL9 1:3~1:6 Negative Online Inquiry
KO29893 AVL9 Knockout cell line (A549) Human AVL9 1:3~1:4 Negative Online Inquiry

Background

AVL9 Gene Knockout Cell Lines are precision-engineered cellular models designed to facilitate the in-depth study of the AVL9 gene’s functions and associated signaling pathways. These cell lines are generated through the CRISPR-Cas9 gene-editing technology, which allows for targeted disruptions in the AVL9 gene, effectively silencing its expression. By exhibiting a complete knockout of AVL9, these cell lines are crucial for understanding the gene’s role in cellular processes such as proliferation, differentiation, and apoptosis.

The key mechanism behind the AVL9 Gene Knockout Cell Lines lies in the targeted modification of genomic DNA. CRISPR-Cas9 introduces double-strand breaks at specific locations in the genome, which the cell attempts to repair through error-prone non-homologous end joining, often resulting in insertion or deletion mutations that disrupt the target gene. Researchers utilize these knockout models to explore the phenotypic consequences of AVL9 loss, thereby providing insights that can lead to new therapeutic strategies for diseases where AVL9 is implicated.

The scientific importance of AVL9 Gene Knockout Cell Lines extends to various fields, including cancer research, neurobiology, and pharmacology. In clinical settings, these cell lines can serve as platforms for drug screening, facilitating the discovery of novel compounds targeting pathways influenced by AVL9. Their application in basic research helps elucidate the molecular mechanisms underlying AVL9's role in cellular homeostasis and disease progression.

One distinct advantage of the AVL9 Gene Knockout Cell Lines is their high specificity and reproducibility, attributes that are essential in generating reliable experimental data. Unlike traditional knockout models, which can be labor-intensive and inconsistent, the CRISPR-based methodology ensures uniformity and efficiency. Moreover, these cell lines integrate seamlessly into existing research workflows, providing a ready-to-use resource for researchers and clinicians alike.

In summary, AVL9 Gene Knockout Cell Lines stand out as a valuable tool for both academic and industrial research, enabling detailed exploration of gene function and its clinical implications. Their unique methodology offers unparalleled reliability, making them an essential asset for advancing scientific understanding and therapeutic development. Our company prides itself on providing high-quality biological research tools backed by extensive expertise in gene editing and cell line development, ensuring that you have the best resources at your disposal for your research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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