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ATXN7L3B Knockout Cell Lines

Gene: ATXN7L3B

Official Full Name: ataxin 7 like 3Bprovided by HGNC

Gene Summary: Involved in regulation of gene expression. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO19537 ATXN7L3B Knockout cell line (HeLa) Human ATXN7L3B 1:3~1:6 Negative Online Inquiry
KO19538 ATXN7L3B Knockout cell line (HCT 116) Human ATXN7L3B 1:2~1:4 Negative Online Inquiry
KO19539 ATXN7L3B Knockout cell line (HEK293) Human ATXN7L3B 1:3~1:6 Negative Online Inquiry
KO19540 ATXN7L3B Knockout cell line (A549) Human ATXN7L3B 1:3~1:4 Negative Online Inquiry

Background

ATXN7L3B Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the ATXN7L3B gene, which is known to play a crucial role in various neurological functions and pathologies, including certain neurodegenerative diseases. These cell lines provide a unique platform for researchers to dissect the biological role of ATXN7L3B and its involvement in molecular mechanisms that may lead to disorders such as spinocerebellar ataxias.

The key functions of the ATXN7L3B knockout cell lines stem from their potential to illuminate gene function through loss-of-function analyses. By eliminating the ATXN7L3B gene, researchers are able to investigate alterations in cellular processes such as protein aggregation, neuronal viability, and signaling pathways that are influenced by the gene in question. This insight is particularly valuable in understanding the etiology of diseases where ATXN7L3B is implicated, facilitating the identification of novel therapeutic targets.

The scientific importance of these knockout cell lines spans various applications in both research and clinical settings. They can serve as invaluable tools in drug screening assays, allowing for the identification of compounds that may mitigate the effects of ATXN7L3B loss. Moreover, the knockouts are critical in functional genomics studies, enabling more profound insights into gene regulatory networks.

In comparison to existing alternatives, ATXN7L3B Gene Knockout Cell Lines offer several unique advantages. They are precisely engineered, ensuring reproducibility and specificity in experimental outcomes. Additionally, they come with comprehensive characterization data, providing researchers with assurance regarding their authenticity and reliability for experimental use.

For researchers and clinicians focused on understanding and manipulating the mechanisms underlying neurodegeneration, the ATXN7L3B Gene Knockout Cell Lines are an indispensable resource that enhances the understanding of cellular dynamics and fosters innovation in therapeutic discovery. Our company is committed to advancing research quality through the provision of high-caliber biological products, leveraging our expertise in genetic engineering to meet the diverse needs of the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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