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ATMIN Knockout Cell Lines

Gene: ATMIN

Official Full Name: ATM interactorprovided by HGNC

Gene Summary: Enables dynein complex binding activity. Involved in positive regulation of DNA-templated transcription. Located in nuclear body. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29514 ATMIN Knockout cell line (HeLa) Human ATMIN 1:3~1:6 Negative Online Inquiry
KO29515 ATMIN Knockout cell line (HCT 116) Human ATMIN 1:2~1:4 Negative Online Inquiry
KO29516 ATMIN Knockout cell line (HEK293) Human ATMIN 1:3~1:6 Negative Online Inquiry
KO29517 ATMIN Knockout cell line (A549) Human ATMIN 1:3~1:4 Negative Online Inquiry

Background

ATMIN Gene Knockout Cell Lines are a suite of precisely engineered cell lines that have undergone genomic editing to disrupt the ATMIN gene, which plays a critical role in DNA damage response and cellular stress management mechanisms. These cell lines are invaluable tools for studying the biological functions of ATMIN, allowing researchers to investigate the gene's contributions to genomic stability, tumorigenesis, and the cellular response to oxidative stress.

The primary function of the ATMIN gene is involved in the cellular pathways that respond to DNA damage, particularly in the maintenance of genomic integrity. The knockout of this gene leads to altered signaling cascades that can elucidate its role in cell cycle regulation and apoptosis. Researchers can use these cell lines to conduct experiments that explore the implications of ATMIN deficiency in cellular behavior, such as increased sensitivity to DNA damaging agents and modifications in cellular metabolism.

The scientific importance of the ATMIN Gene Knockout Cell Lines extends to their applications in both basic research and clinical settings. For instance, they offer a platform for drug discovery in cancer therapeutics and provide insights into the development of diseases characterized by genomic instability. These cell lines can contribute to the understanding of novel therapeutic targets and the molecular mechanisms underpinning various malignancies.

One of the unique selling points of our ATMIN Gene Knockout Cell Lines is the precision with which the gene was disrupted, ensuring reliable results and reproducibility. Unlike existing alternatives, these cell lines are thoroughly validated for consistent performance in diverse experimental contexts, making them essential for professionals seeking high-quality reagents.

Researchers and clinicians will find our ATMIN Gene Knockout Cell Lines particularly valuable as they facilitate groundbreaking studies that drive innovation and advance our understanding of complex biological processes. Furthermore, they are supported by comprehensive technical documentation and customer service, ensuring that users can maximize their potential in research endeavors.

With years of experience in developing cutting-edge biological products, our company is dedicated to providing researchers with reliable and effective tools, like the ATMIN Gene Knockout Cell Lines, to accelerate scientific discovery and improve clinical outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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