Gene: ATF7IP
Official Full Name: activating transcription factor 7 interacting proteinprovided by HGNC
Gene Summary: ATF7IP is a multifunctional nuclear protein that associates with heterochromatin. It can act as a transcriptional coactivator or corepressor depending upon its binding partners (summary by Liu et al., 2009 [PubMed 19106100]).[supplied by OMIM, Nov 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20684 | ATF7IP Knockout cell line (HeLa) | Human | ATF7IP | 1:3~1:6 | Negative | Online Inquiry |
KO20685 | ATF7IP Knockout cell line (HCT 116) | Human | ATF7IP | 1:2~1:4 | Negative | Online Inquiry |
KO20686 | ATF7IP Knockout cell line (HEK293) | Human | ATF7IP | 1:3~1:6 | Negative | Online Inquiry |
KO20687 | ATF7IP Knockout cell line (A549) | Human | ATF7IP | 1:3~1:4 | Negative | Online Inquiry |
ATF7IP Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to facilitate the study of the ATF7IP gene, which is pivotal in various cellular processes, including transcriptional regulation and stress response. By eliminating the ATF7IP gene, researchers can explore its functional roles and the biological pathways it influences, enabling a deeper understanding of its implications in disease states such as cancer and metabolic disorders.
The primary function of these cell lines is to provide a controlled environment for examining the phenotypic and molecular characteristics resulting from the absence of ATF7IP. This gene knockout mechanism allows for detailed analyses of gene function and the pathways affected by its loss, utilizing CRISPR-Cas9 gene editing technology for precise modifications. Researchers can employ these models in various assays, including proliferation, apoptosis, and signaling studies, thus generating comprehensive data about cellular responses that are mediated by ATF7IP.
The scientific importance of ATF7IP Gene Knockout Cell Lines lies in their utility across a range of research and clinical applications. They are invaluable tools for investigating the gene's roles in cellular stress responses and have potential therapeutic implications in developing targeted treatments for related diseases. By utilizing these knockout models, researchers can decipher novel molecular mechanisms that contribute to disease, thereby advancing the field of genomics and personalized medicine.
What sets our ATF7IP Gene Knockout Cell Lines apart from alternatives on the market is their high specificity, consistent performance, and robust validation process. Each cell line is rigorously characterized for a complete knockout of ATF7IP, ensuring reliability in experimental outcomes. Additionally, our commitment to providing comprehensive technical support and user-friendly protocols enhances the product's accessibility and ease of use for researchers.
In summary, ATF7IP Gene Knockout Cell Lines serve as a critical asset for scientists and clinicians interested in understanding the complexities of ATF7IP-related mechanisms in health and disease. Our company is dedicated to advancing biological research with high-quality, reliable products, backed by our expertise in gene editing technologies. With these cell lines, users gain a powerful tool to push the boundaries of biological discovery and therapeutic development.
Please note that all services are for research use only. Not intended for any clinical use.
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