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ASB3 Knockout Cell Lines

Gene: ASB3

Official Full Name: ankyrin repeat and SOCS box containing 3provided by HGNC

Gene Summary: The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jan 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22983 ASB3 Knockout cell line (HeLa) Human ASB3 1:3~1:6 Negative Online Inquiry
KO22984 ASB3 Knockout cell line (HCT 116) Human ASB3 1:2~1:4 Negative Online Inquiry
KO22985 ASB3 Knockout cell line (HEK293) Human ASB3 1:3~1:6 Negative Online Inquiry
KO22986 ASB3 Knockout cell line (A549) Human ASB3 1:3~1:4 Negative Online Inquiry

Background

ASB3 Gene Knockout Cell Lines are genetically engineered cell lines designed to selectively disable the ASB3 gene, a member of the Ankyrin Repeat and SOCS Box (ASB) family that plays a crucial role in various cellular processes, including protein degradation, signal transduction, and cellular differentiation. By employing CRISPR/Cas9 genome editing technology, these cell lines facilitate targeted studies of ASB3 functions, enabling researchers to examine its influence on cellular behavior and its contribution to diverse biological pathways.

The key function of ASB3 Gene Knockout Cell Lines lies in their ability to elucidate the biological roles of ASB3 in health and disease. By knocking out ASB3, researchers can explore the downstream effects on signaling cascades, gene expression profiles, and protein interactions. This targeted approach allows for precise manipulation of cellular environments, providing insights into the gene's implications in various conditions such as cancer, metabolic disorders, and developmental abnormalities.

The scientific importance of these cell lines is underscored by their wide-ranging applications in both research and clinical settings. They serve as invaluable tools for drug discovery, allowing for screening potential therapeutics that target ASB3-related pathways. Additionally, they contribute to basic research aiming to understand the fundamental mechanisms governing cell physiology and pathology.

What sets ASB3 Gene Knockout Cell Lines apart from other genetic models is their high specificity and efficiency in gene editing, which minimizes off-target effects often seen in traditional methods. Furthermore, these cell lines come with robust characterization data, ensuring researchers can confidently interpret their experimental outcomes.

For researchers and clinicians alike, the value of ASB3 Gene Knockout Cell Lines resides in their potential to accelerate discoveries, inform therapeutic strategies, and ultimately contribute to advancements in personalized medicine. By integrating these knockout models into your studies, you can unlock new avenues for understanding ASB3’s role in cellular dynamics, leading to innovative research outcomes.

With proven expertise in gene editing technology and a dedication to supporting scientific discovery, our company stands at the forefront of providing high-quality biological products tailored for researchers seeking to expand their understanding of complex biological systems.

Please note that all services are for research use only. Not intended for any clinical use.

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