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ART5 Knockout Cell Lines

Gene: ART5

Official Full Name: ADP-ribosyltransferase 5provided by HGNC

Gene Summary: The protein encoded by this gene belongs to the ARG-specific ADP-ribosyltransferase family. Proteins in this family regulate the function of target proteins by attaching ADP-ribose to specific amino acid residues in their target proteins. The mouse homolog lacks a glycosylphosphatidylinositol-anchor signal sequence and is predicted to be a secretory enzyme. Several transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30471 ART5 Knockout cell line (HCT 116) Human ART5 1:2~1:4 Negative Online Inquiry
KO30472 ART5 Knockout cell line (HEK293) Human ART5 1:3~1:6 Negative Online Inquiry

Background

ART5 Gene Knockout Cell Lines are advanced biological tools designed to facilitate the study of gene function and the molecular pathways implicated in various biological processes. These engineered cell lines are created through precise gene editing techniques, most commonly utilizing CRISPR/Cas9 technology, to produce targeted deletions within the ART5 gene. By disrupting the normal expression of ART5, these cell lines provide researchers with invaluable insights into the gene's role in cellular functions, signaling pathways, and disease mechanisms.

The chief mechanism behind the utility of ART5 Gene Knockout Cell Lines lies in the ability to model specific genetic alterations in vitro. This enables scientists to analyze the phenotypic manifestations resulting from the gene disruption, assess compensatory biological processes, and unravel the complexities of gene interactions. These lines can be used to investigate various applications, including cancer research, metabolic studies, and investigations into immune responses, making them indispensable tools in both research laboratories and clinical settings.

Compared to traditional methods of gene disruption, such as stable transfection or viral vector delivery, the ART5 Gene Knockout Cell Lines stand out due to their high specificity and efficiency in gene editing. These lines are rigorously validated for genomic integrity, ensuring reliable and reproducible results. Additionally, their ease of use allows for rapid adaptation across various experimental platforms, fostering flexibility in research design.

For researchers and clinicians looking to deepen their understanding of gene function and its implications in health and disease, ART5 Gene Knockout Cell Lines offer a unique solution. Their capacity to provide clear mechanistic insights into the effects of gene disruption heralds potential advancements in therapeutic strategies, aiding in the development of novel treatments.

Our company specializes in producing high-quality biological products, including custom and ready-to-use gene knockout cell lines, demonstrating our commitment to supporting the life sciences community with precision tools that drive innovation and discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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