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ARSK Knockout Cell Lines

Gene: ARSK

Official Full Name: arylsulfatase family member Kprovided by HGNC

Gene Summary: Sulfatases (EC 3.1.5.6), such as ARSK, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules (Sardiello et al., 2005 [PubMed 16174644]).[supplied by OMIM, Mar 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21517 ARSK Knockout cell line (HeLa) Human ARSK 1:3~1:6 Negative Online Inquiry
KO21518 ARSK Knockout cell line (HCT 116) Human ARSK 1:2~1:4 Negative Online Inquiry
KO21519 ARSK Knockout cell line (HEK293) Human ARSK 1:3~1:6 Negative Online Inquiry
KO21520 ARSK Knockout cell line (A549) Human ARSK 1:3~1:4 Negative Online Inquiry

Background

ARSK Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the ARSK (arabinofuranosyl transferase), which plays a critical role in nucleotide metabolism. These knockout cell lines allow researchers to investigate the functional implications of ARSK deficiency, facilitating the study of several biological processes, including cellular signaling, metabolism, and disease mechanisms.

The primary mechanism of action for these cell lines involves the targeted disruption of the ARSK gene using CRISPR-Cas9 technology. This approach ensures precise genetic editing, allowing for the interrogation of gene function and its contribution to cellular phenotypes. By eliminating ARSK expression, researchers can elucidate its role in cellular pathways, providing insight into pathological conditions where ARSK may play a pivotal role.

The scientific importance of ARSK Gene Knockout Cell Lines extends to various research areas, including cancer biology, metabolic disorders, and immunology. Understanding how the absence of ARSK affects cellular behavior can uncover novel therapeutic targets or enhance biomarker discovery, making these models invaluable for drug development and precision medicine.

One key advantage of the ARSK Gene Knockout Cell Lines over traditional models is the specificity and efficiency they offer through precise gene editing. This technology reduces off-target effects commonly seen in earlier gene knockout methods, leading to more reliable and reproducible results. Furthermore, their ease of use and compatibility with standard culture techniques allow for seamless integration into existing research workflows.

For researchers and clinicians, these cell lines represent a powerful tool to unlock the complexities of ARSK-related pathways, accelerating advancements in both basic and applied sciences. Investing in ARSK Gene Knockout Cell Lines enables scientists to push the boundaries of knowledge and discover new opportunities for treatment strategies.

Our company specializes in providing high-quality biological products tailored for groundbreaking research. With a commitment to innovation and scientific excellence, we ensure that our offerings, like the ARSK Gene Knockout Cell Lines, are crafted with precision and designed to meet the evolving needs of the research community.

Please note that all services are for research use only. Not intended for any clinical use.

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