Gene: ARRDC4
Official Full Name: arrestin domain containing 4provided by HGNC
Gene Summary: Enables ubiquitin-like ligase-substrate adaptor activity. Involved in positive regulation of interferon-beta production and protein K63-linked ubiquitination. Acts upstream of or within positive regulation of ubiquitin-protein transferase activity. Located in endosome and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23327 | ARRDC4 Knockout cell line (HeLa) | Human | ARRDC4 | 1:3~1:6 | Negative | Online Inquiry |
KO23328 | ARRDC4 Knockout cell line (HCT 116) | Human | ARRDC4 | 1:2~1:4 | Negative | Online Inquiry |
KO23329 | ARRDC4 Knockout cell line (HEK293) | Human | ARRDC4 | 1:3~1:6 | Negative | Online Inquiry |
ARRDC4 Gene Knockout Cell Lines are engineered cellular models that feature a targeted inactivation of the ARRDC4 gene, which is crucial for understanding its role in various biological processes and disease states. This product enables researchers to explore the specific functions of ARRDC4 by providing a system in which its expression is completely disrupted, allowing for detailed studies of associated signaling pathways, cellular responses, and potential impacts on disease progression.
The key function of ARRDC4 revolves around its involvement in cellular processes such as endocytosis, protein trafficking, and regulation of cell signaling. By utilizing these knockout cell lines, scientists can elucidate the molecular mechanisms underlying the ARRDC4 gene, furthering our understanding of its implications in conditions like cancer, cardiovascular diseases, and metabolic disorders. The absence of ARRDC4 in these cell lines allows researchers to investigate how its loss affects cellular dynamics and intercellular communication, which can reveal novel therapeutic targets.
The scientific importance of ARRDC4 Gene Knockout Cell Lines lies in their versatility for research, ranging from basic biology to translational studies. These models provide a reliable platform for pharmacological testing, biomarker discovery, and gene function analyses, making them invaluable in both research laboratories and clinical settings.
Unlike standard cell lines that may exhibit partial or context-dependent expression of ARRDC4, these knockout lines ensure a consistent, complete loss of function. This specificity not only enhances the reliability of experimental outcomes but also significantly reduces variability, making findings easier to interpret. Furthermore, the ARRDC4 knockouts are generated under rigorous quality control protocols, ensuring that researchers receive a high-fidelity model for their studies.
For researchers and clinicians alike, investing in ARRDC4 Gene Knockout Cell Lines translates to an opportunity to advance scientific knowledge and therapeutic development in a streamlined fashion. The ability to examine the direct effects of gene depletion facilitates more accurate experimental design, leading to clearer insights into ARRDC4's biological significance.
Our company specializes in providing high-quality genetic models tailored for advanced research applications, leveraging our expertise in gene editing technologies to deliver products that meet the evolving needs of the scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
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