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ARRDC3 Knockout Cell Lines

Gene: ARRDC3

Official Full Name: arrestin domain containing 3provided by HGNC

Gene Summary: This gene encodes a member of the arrestin family of proteins, which regulate G protein-mediated signaling. The encoded protein is thought to act as a regulator of breast cancer growth and progression by binding to a phosphorylated form of integrin beta4, a tumor-related antigen, targeting the integrin for internalization and degradation. [provided by RefSeq, Jul 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO09383 ARRDC3 Knockout cell line (HeLa) Human ARRDC3 1:3~1:6 Negative Online Inquiry
KO09384 ARRDC3 Knockout cell line (HCT 116) Human ARRDC3 1:2~1:4 Negative Online Inquiry
KO09385 ARRDC3 Knockout cell line (HEK293) Human ARRDC3 1:3~1:6 Negative Online Inquiry
KO09386 ARRDC3 Knockout cell line (A549) Human ARRDC3 1:3~1:4 Negative Online Inquiry

Background

ARRDC3 Gene Knockout Cell Lines are specially engineered cellular models that have undergone targeted gene knockout of the ARRDC3 gene, pivotal in various cellular processes, including endocytosis, cellular signaling, and membrane dynamics. By precisely disabling the ARRDC3 gene, researchers can create a controlled environment to investigate the gene's function and its broader implications in cellular behavior and disease mechanisms.

The key function of these knockout cell lines lies in their ability to elucidate the biological consequences of ARRDC3 disruption. ARRDC3 plays a significant role in the post-receptor signaling pathways and contributes to adaptive responses in different biological contexts. Utilizing these cell lines, scientists can employ a multitude of experimental techniques, including Western blotting, quantitative PCR, and flow cytometry, to analyze alterations in protein expression patterns, signaling pathways, and cellular processes, thus providing insights into its role in health and disease.

The scientific importance of ARRDC3 Gene Knockout Cell Lines extends to research environments focusing on cancer biology, neurobiology, and metabolic disorders where ARRDC3 is implicated. These models serve as invaluable tools for drug discovery and therapeutic targeting, allowing researchers to screen potential pharmacological agents and assess their efficacy in the absence of ARRDC3 activity.

When compared to alternative cell lines or genetic models, the ARRDC3 knockout cell lines offer a unique and specific insight into the gene's role, facilitating more focused research efforts. Their precision in gene editing provides novelty, fostering reproducibility and reliability in experimental results, essential for advancing scientific knowledge.

The value of these knockout cell lines to researchers and clinicians is immense, as they deliver a robust platform to drive hypothesis generation, experimental design, and potential clinical applications. As scientists strive to understand complex diseases, the ARRDC3 Gene Knockout Cell Lines provide an essential resource for uncovering new therapeutic targets and developing innovative strategies to combat disease.

As a leader in the production of specialized biological products, our company prides itself on delivering high-quality, rigorously validated cellular models that empower the scientific community, supporting groundbreaking research and clinical advancements across multiple fields.

Please note that all services are for research use only. Not intended for any clinical use.

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