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ARMC5 Knockout Cell Lines

Gene: ARMC5

Official Full Name: armadillo repeat containing 5provided by HGNC

Gene Summary: This gene encodes a member of the ARM (armadillo/beta-catenin-like repeat) superfamily. The ARM repeat is a tandemly repeated sequence motif with approximately 40 amino acid long. This repeat is implicated in mediating protein-protein interactions. The encoded protein contains seven ARM repeats. Mutations in this gene are associated with primary bilateral macronodular adrenal hyperplasia, which is also known as ACTH-independent macronodular adrenal hyperplasia 2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO06556 ARMC5 Knockout cell line (HeLa) Human ARMC5 1:3~1:6 Negative Online Inquiry
KO06557 ARMC5 Knockout cell line (HCT 116) Human ARMC5 1:2~1:4 Negative Online Inquiry
KO06558 ARMC5 Knockout cell line (HEK293) Human ARMC5 1:3~1:6 Negative Online Inquiry
KO06559 ARMC5 Knockout cell line (A549) Human ARMC5 1:3~1:4 Negative Online Inquiry

Background

ARMC5 Gene Knockout Cell Lines are genetically modified cell lines specifically designed to investigate the biological functions and pathways associated with the ARMC5 gene. These lines are created using CRISPR/Cas9 gene editing technology, allowing precise and efficient disruption of the ARMC5 gene, which has been implicated in various physiological processes, including cellular signaling and tumor suppression. By knocking out the ARMC5 gene, researchers can gain insights into its role in cellular mechanisms, disease progression, and potential therapeutic targets.

The primary function of these cell lines is to facilitate the study of genetic contributions to specific phenotypes by enabling the analysis of altered cellular behaviors that arise from the absence of ARMC5. Mechanistically, the loss of ARMC5 may affect cellular proliferation, apoptosis, and differentiation, thereby offering a platform for exploring how these changes influence diseases, particularly cancer. The assay-ready format of these knockout cell lines ensures compatibility with numerous experimental setups, from high-throughput screenings to gene expression analyses.

Scientifically, ARMC5 Gene Knockout Cell Lines are of paramount importance in both basic and applied research. Their use can advance our understanding of genetic disorders, cancer biology, and therapeutic response mechanisms. In clinical settings, these cell lines can serve as valuable tools for drug testing and personalized medicine approaches, supporting targeted therapies for conditions linked to ARMC5 dysfunction.

Compared to alternative models, ARMC5 Gene Knockout Cell Lines offer several advantages, including higher specificity in gene targeting, reliability in experimental applications, and a rapid timeline for results. They are also supported by comprehensive documentation, detailed protocols, and robust customer support, ensuring researchers can seamlessly integrate these cell lines into their workflows.

For researchers and clinicians aiming to unravel the complexities of the ARMC5 gene and its implications in health and disease, these knockout cell lines represent an invaluable resource. With a commitment to innovation and scientific excellence, our company provides high-quality biological products that empower research and enhance understanding in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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