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ARMC10 Knockout Cell Lines

Gene: ARMC10

Official Full Name: armadillo repeat containing 10provided by HGNC

Gene Summary: This gene encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3. [provided by RefSeq, Sep 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25366 ARMC10 Knockout cell line (HeLa) Human ARMC10 1:3~1:6 Negative Online Inquiry
KO25367 ARMC10 Knockout cell line (HCT 116) Human ARMC10 1:2~1:4 Negative Online Inquiry
KO25368 ARMC10 Knockout cell line (HEK293) Human ARMC10 1:3~1:6 Negative Online Inquiry
KO25369 ARMC10 Knockout cell line (A549) Human ARMC10 1:3~1:4 Negative Online Inquiry

Background

ARMC10 Gene Knockout Cell Lines are advanced biological models that enable researchers to investigate the functions of the ARMC10 gene by creating a complete loss-of-function scenario. These cell lines are generated using CRISPR-Cas9 technology, which introduces targeted modifications to the genome, effectively knocking out the ARMC10 gene. This precise alteration allows for the study of gene-specific pathways and cellular processes, providing insights into the gene's role in various biological contexts.

The primary mechanism by which these cell lines operate is their ability to mimic genetic aberrations found in disease states. By eliminating the ARMC10 gene, researchers can evaluate its influence on cell proliferation, differentiation, and apoptosis, offering a unique platform for studying its implications in cancer biology, neurodevelopmental disorders, and metabolic syndromes. The versatility of ARMC10 knockout cell lines allows for their application across diverse areas of research, including pharmacology, toxicology, and molecular genetics.

One of the standout features of ARMC10 Gene Knockout Cell Lines is their specificity and reproducibility in knockout efficiency, reducing variability often seen with other genetic manipulation methods. Compared to alternative gene-editing approaches, such as RNA interference, these knockout lines provide a permanent genetic alteration, leading to more reliable and consistent results over extended experimental periods.

For researchers and clinicians, utilizing ARMC10 Gene Knockout Cell Lines translates to a robust platform for exploring novel therapeutic targets and developing new treatment strategies. By elucidating the functional roles of the ARMC10 gene, scientists can contribute vital knowledge towards improving health outcomes, particularly in diseases directly linked to this gene.

Our company specializes in providing high-quality gene knockout cell lines backed by rigorous scientific research and validation. With a commitment to advancing biological understanding, we equip researchers with the tools necessary to push the boundaries of knowledge and exploration in the field of genetics and cell biology.

Please note that all services are for research use only. Not intended for any clinical use.

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