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ARHGAP40 Knockout Cell Lines

Gene: ARHGAP40

Official Full Name: Rho GTPase activating protein 40provided by HGNC

Gene Summary: Predicted to enable GTPase activator activity. Predicted to be involved in regulation of actin filament polymerization and regulation of small GTPase mediated signal transduction. Predicted to be located in cytosol. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO19711 ARHGAP40 Knockout cell line (HCT 116) Human ARHGAP40 1:2~1:4 Negative Online Inquiry

Background

ARHGAP40 Gene Knockout Cell Lines are genetically modified cellular systems that enable the functional study of the ARHGAP40 gene, a significant regulator of Rho GTPases involved in various cellular processes, including cytoskeletal dynamics, cell proliferation, and migration. These knockout cell lines are created using advanced CRISPR/Cas9 technology, which precisely disrupts the ARHGAP40 gene expression, allowing researchers to investigate the gene's role in cellular signaling pathways and its implications in diseases such as cancer and fibrosis.

The primary function of ARHGAP40 involves modulating the activity of Rho GTPases, particularly in the context of actin cytoskeleton organization. By knocking out this gene, researchers can elucidate the effects on cell morphology, migration patterns, and overall cellular behavior, thereby providing insights into how ARHGAP40 impacts cellular homeostasis and pathophysiology. These studies have broader implications in immunology, neurology, and cancer biology, making these cell lines invaluable tools for researchers.

In clinical and research settings, the ARHGAP40 Gene Knockout Cell Lines are critical for drug development and therapeutic target identification. Their unique ability to mimic physiological conditions of ARHGAP40 deficiency allows for a more accurate assessment of potential treatments and understanding of disease mechanisms. Compared to traditional cell lines, these knockout models provide a more straightforward approach to studying gene function, enabling quicker and more effective experimental outcomes.

Furthermore, researchers and clinicians seeking to gain a deeper understanding of cellular pathways will find the ARHGAP40 Gene Knockout Cell Lines particularly advantageous. With robust validation and comprehensive support, this product stands out as an essential resource for advancing scientific inquiry and therapeutic innovations. Our company prides itself on utilizing cutting-edge gene editing technologies and rigorous quality control to provide high-quality biological products that support the scientific community in their quest for knowledge and breakthroughs.

Please note that all services are for research use only. Not intended for any clinical use.

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