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ARFIP2 Knockout Cell Lines

Gene: ARFIP2

Official Full Name: ARF interacting protein 2provided by HGNC

Gene Summary: Enables several functions, including GTP-dependent protein binding activity; membrane curvature sensor activity; and phosphatidylinositol-4-phosphate binding activity. Involved in actin cytoskeleton organization; mitophagy; and protein localization to phagophore assembly site. Located in several cellular components, including nucleolus; ruffle; and trans-Golgi network membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29022 ARFIP2 Knockout cell line (HeLa) Human ARFIP2 1:3~1:6 Negative Online Inquiry
KO29023 ARFIP2 Knockout cell line (HCT 116) Human ARFIP2 1:2~1:4 Negative Online Inquiry
KO29024 ARFIP2 Knockout cell line (HEK293) Human ARFIP2 1:3~1:6 Negative Online Inquiry
KO29025 ARFIP2 Knockout cell line (A549) Human ARFIP2 1:3~1:4 Negative Online Inquiry

Background

ARFIP2 Gene Knockout Cell Lines are specialized cellular models designed to facilitate the study of the ARFIP2 gene's role in various biological processes. These cell lines are genetically engineered to have a complete disruption of the ARFIP2 gene, allowing researchers to analyze the resulting phenotypic changes and investigate the gene's functions, signaling pathways, and interactions within the cellular environment.

The key function of ARFIP2, or ARF interacting protein 2, is its involvement in the regulation of intracellular trafficking and endosomal dynamics, impacting processes such as autophagy and membrane receptor recycling. By utilizing our gene knockout cell lines, researchers can explore the mechanistic roles of ARFIP2 in cell proliferation, differentiation, and response to environmental stimuli, thereby uncovering potential implications in diseases such as cancer and neurodegeneration.

This product holds significant scientific importance in both research and clinical settings. In academic research, ARFIP2 knockout models enable scientists to dissect molecular pathways that contribute to disease mechanisms, creating opportunities for the identification of new therapeutic targets. Clinically, understanding the dysfunction of ARFIP2 may lead to novel interventions in pathologies where this gene is implicated.

The ARFIP2 Gene Knockout Cell Lines stand out from alternative products on the market due to their comprehensive validation for gene disruption and demonstrated consistency in experimental reproducibility. Each cell line is accompanied by detailed characterization data, ensuring that researchers can confidently interpret results. Additionally, our commitment to quality ensures that these models maintain genetic stability and functional integrity over multiple passages.

For researchers and clinicians focused on elucidating the complexities of cellular mechanisms or developing targeted therapies, our ARFIP2 Gene Knockout Cell Lines provide a powerful tool to advance their scientific endeavors. Leveraging years of expertise in cellular biology and genetics, our company offers high-quality biological products that support cutting-edge research and contribute to scientific advancement.

Please note that all services are for research use only. Not intended for any clinical use.

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